Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping the cells…
Category: 5. Biology
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Aging lung cells drive severe inflammation in flu and COVID
Older adults are much more likely to become seriously ill from flu or COVID because aging lung cells can drive excessive immune responses, according to a new study led by researchers at UC San Francisco.
The findings enhance the…
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Diverse biobank study links genetics to disease risk and treatment
A new study by UCLA Health published in Cell presents a major advancement in the future of personalized medicine by pinpointing new connections between people’s genes, disease risk and medicine response by using a clinically…
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Land animals evolved from ocean ancestors—new study unravels the genetics behind the transition
The transition from water to land is a question that still intrigues scientists. Those ancient organisms would have needed to adapt to several new challenges to life out of water. So, how did they do it?
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A controllable human spinal cord model with full dorsoventral patterning
Gouti, M., Metzis, V. & Briscoe, J. The route to spinal cord cell types: a tale of signals and switches. Trends Genet. 31, 282–289 (2015).
Sagner, A. & Briscoe, J. Establishing neuronal…
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TUFM: a central regulator in mitochondrial quality control and beyond
Richter D, Lipmann F. Separation of mitochondrial and cytoplasmic peptide chain elongation factors from yeast. Biochemistry. 1970;9:5065–70.
Kuhlman P, Palmer JD. Isolation, expression, and…
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Neoantigen evolution and response to checkpoint inhibitor immunotherapy in colorectal cancer
Dong, H. et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. 8, 793–800 (2002).
Ansell, S. M. et al. PD-1 blockade with nivolumab in…
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The Sirt2–Nur77 axis regulates muscle stem cell quiescence and senescence via epigenetic–metabolic synergy
Sousa-Victor P, García-Prat L, Muñoz-Cánoves P. Control of satellite cell function in muscle regeneration and its disruption in ageing. Nat Rev Mol Cell Biol. 2022;23:204–26.
Kahn RE,…
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Identification of an R2R3-MYB gene regulating tepal background coloration in Tricyrtis sp.
Otani, M. et al. Comprehensive isolation and expression analysis of the flavonoid biosynthesis-related genes in Tricyrtis spp. Biol. Plant. 62, 684–692. https://doi.org/10.1007/s10535-018-0802-7 (2018).
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Accumulation of virtual tokens towards a jackpot reward enhances performance and value encoding in dorsal anterior cingulate cortex
Kahneman, D. & Tversky, A. Prospect Theory: An Analysis of Decision under Risk. Econ. Soc. 47, 263–291 (1979).
Anke Braun, X., Urai, A. E., Tobias, X. & Donner, H. Adaptive history biases result from confidence-weighted accumulation of past…
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