This study was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [grant numbers 17H06401 (HK and MI), 19H02840, 22H04901, 23H04882, 24H00493 (all…
Category: 5. Biology
-
Author Correction: The genetic and environmental composition of socioeconomic status in Norway
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
Continue Reading
-
PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
Clinical samples and experimental cellular cultures
Clinical samples of ccRCC, including tumor and adjacent normal kidney tissues, were sourced from the Department of Urology at Union Hospital, affiliated with Tongji Medical College in Wuhan,…
Continue Reading
-
Kupffer cell reprogramming in embryos explains metabolic disorders in offspring
Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves. A new study from the University of Bonn offers an explanation for this phenomenon. In obese mice,…
Continue Reading
-
New insights into how inhalational anesthetics induce general anesthesia
Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their anesthetic has not been fully…
Continue Reading
-
New molecular atlas offers unprecedented insight into human kidney function
The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a groundbreaking molecular mapping project that could reshape our understanding of renal health. Despite advances in transcriptomics and…
Continue Reading
-
Yale researchers triple precision and efficiency in genome editing
The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing technologies can alter or delete single…
Continue Reading
-
Maternal Hypertension and Childhood Seizure Risk
A study published in the Journal of Clinical Investigation seeks to understand the relationship between maternal hypertensive disorders of pregnancy (HDP) and the risk of seizures and epilepsy in offspring,…
Continue Reading
-
Advances in HIV Vaccines & Treatment Come with Serious Funding Cuts
There is still no cure or effective vaccine for HIV-1, which remains a public health threat. But scientists have opened up new possibilities in HIV treatment and vaccine development.
A Step Towards a…
Continue Reading