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Category: 5. Biology

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  • Epigenetic suppression of synovial inflammation and osteoclast differentiation in rheumatoid arthritis by I-BET762

  • Araki, Y. et al. Histone methylation and STAT-3 differentially regulate interleukin-6-induced matrix metalloproteinase gene activation in rheumatoid arthritis synovial fibroblasts. Arthritis Rheumatol. 68(5), 1111–1123 (2016).

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  • Automated mapping of DNA replication fork progression in human cells with ForkML

  • Saxena, S. & Zou, L. Hallmarks of DNA replication stress. Mol. Cell 82, 2298–2314 (2022).

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  • Wang, N., Xu, S. & Egli, D. Replication stress in mammalian embryo development, differentiation, and…

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  • Antibacterial, antibiofilm, and metabolomic profiling of the novel freshwater fungi Longipedicellata megafusiformis and Wicklowia fusiformispora

  • El-Elimat, T. et al. Freshwater fungi as a source of chemical diversity: A review. J. Nat. Prod. 84, 464–488 (2021).

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  • Tsui, C. K. M., Hyde, K. D. & Hodgkiss, I. J. Biodiversity of fungi on…

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  • The E3 ligases Itch and WWP2 regulate autoimmune neuroinflammation by controlling TH2 to TH17 cell conversion via interleukin-4-STAT5 axis in mice

  • Tuzlak, S. et al. Repositioning TH cell polarization from single cytokines to complex help. Nat. Immunol. 22, 1210–1217 (2021).

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  • Zhu, J. & Paul, W. E. Peripheral CD4 + T-cell…

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  • Author Correction: The ‘photosynthetic C1 pathway’ links carbon assimilation and growth in California poplar

    Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…

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  • A novel homozygous splicing variant in FRA10AC1: further delineation of the phenotype

    A novel homozygous splicing variant in FRA10AC1: further delineation of the phenotype

    Biallelic variants in FRA10AC1 have been identified as the cause of a neurodevelopmental disorder with growth retardation, dysmorphic features and corpus callosum abnormalities (MIM: # 620113). Ten patients from 6 unrelated families have been…

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  • Genetic divergence and lower frequencies of insecticide resistance markers in the novel Anopheles gambiae Bissau molecular form in The Gambia

  • Tennessen, J. A. et al. A population genomic unveiling of a new cryptic mosquito taxon within the malaria-transmitting Anopheles Gambiae complex. Mol. Ecol. 30, 775–790 (2021).

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  • Yeo, H., Lin,…

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  • Structural basis of CSN-mediated SCF deneddylation

  • Harper, J. W. & Schulman, B. A. Cullin-RING ubiquitin ligase regulatory circuits: a quarter century beyond the F-box hypothesis. Annu. Rev. Biochem. 90, 403–429 (2021).

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  • Komander, D. & Rape,…

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  • Plant fucosyltransferase FUT11 distorts the sugar acceptor to catalyze via a transient oxocarbenium intermediate mechanism

  • Mohanty, S., Chaudhary, B. P. & Zoetewey, D. Structural insight into the mechanism of N-linked glycosylation by oligosaccharyltransferase. Biomolecules 10, 624 (2020).

  • Schjoldager, K. T., Narimatsu, Y., Joshi, H. J. & Clausen, H. Global view of…

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