A deadly fungus linked to deaths in archeologists excavating ancient tombs has…
Category: 5. Biology
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Flies on dairy farms act as hidden carriers of superbugs and zoonotic threats
A genomic deep dive shows that manure-feeding flies may be silent super-spreaders, transferring and amplifying resistant pathogens from livestock waste into the farm environment.
Study: Genomic evidence for flies as carriers of…
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Gating and noelin clustering of native Ca2+-permeable AMPA receptors
AMPA-type ionotropic glutamate receptors (AMPARs) are integral to fast excitatory synaptic transmission and play vital roles in synaptic plasticity, motor coordination, learning, and memory1. While extensive structural studies have been conducted…
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P-type ATPase magnesium transporter MgtA acts as a dimer
Moomaw, A. S. & Maguire, M. E. The unique nature of Mg2+ channels. Physiology 23, 275–285 (2008).
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Franken, G. A. C., Huynen, M. A., Martínez-Cruz, L. A.,…
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A class of benzofuranoindoline-bearing heptacyclic fungal RiPPs with anticancer activities
Bharate, S. B. & Lindsley, C. W. Call for papers: natural products driven medicinal chemistry. J. Med. Chem. 66, 16455–16456 (2023).
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Newman, D. J. & Cragg, G. M….
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New-to-nature biocompatible chemistry for plastic waste upcycling
New-to-nature biocompatible chemistry for plastic waste upcycling
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Apical size reduction by macropinocytosis alleviates tissue crowding
Transgenic Xenopus and mRNA embryo injections
In vitro fertilizations were performed using standard protocols47,48,49,50 that have been approved by the Northwestern University Institutional Animal Care and Use Committee (IS00027128). Transgenic…
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Expanding the utility of precision oncology knowledge bases
Suehnholz, S. P. et al. Quantifying the expanding landscape of clinical actionability for patients with cancer. Cancer Discov. 14, 49–65 (2024).
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Yin,…
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Super-enhancers orchestrate transcriptional dysregulation and metabolic reprogramming in uveal melanoma
Cell culture
The normal human melanocyte cell line PIG1 was provided by the Department of Ophthalmology, Peking University Third Hospital (Beijing, China). The UM cell lines 92.1 and MP46 and the human retinal pigment epithelial cell lines ARPE19…
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BRCA1 expression in ovarian cancer and its relationship with clinicopathological characteristics and prognosis
General data
Cancer tissue specimens, para-carcinoma tissue specimens and clinical data of 195 ovarian cancer patients diagnosed in our hospital from January 2016 to August 2021 were collected and analyzed. Among them, 101 cases were younger than…
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