Recent findings shed new light on the critical role of TET1, a pivotal player in epigenetic regulation, in the development and progression of various clinical diseases. As an enzyme responsible for DNA demethylation, TET1 influences…
Category: 5. Biology
-
LINE-1 elements found essential for early embryonic development
A new review from Genes and Diseases sheds light on the pivotal role of LINE-1 elements in preimplantation development and totipotency, revealing their essential contributions to early mammalian embryogenesis. Once considered mere…
Continue Reading
-
Enhanced Genomics and The ALBORADA Drug Discovery Institute partner to accelerate Alzheimer’s drug discovery
Enhanced Genomics (‘Enhanced’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced a strategic partnership with The…
Continue Reading
-
Scientists use base editing to repair mitochondrial DNA mutations
In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The results, published June 24th in the…
Continue Reading
-
Health Risks from Fecal Transplants Call for Caution
New findings suggest that regional microbial mismatches from fecal microbiota transplants (FMT) can lead to unintended consequences for recipients. The corresponding study was published in Cell.
“I think…
Continue Reading
-
How a novel reaction in E. coli helps recycle plastic into paracetamol
Scientists harness a new-to-nature reaction in E. coli to turn discarded plastics into life-saving medicines, charting a sustainable path for chemical manufacturing.
a, A comparison of strategies for C–N bond formation via Lossen…
Continue Reading
-
Scientists create ALS on a chip to uncover disease clues
Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective…
Continue Reading
-
New technology unlocks cellular ancestry with DNA barcodes
A landmark study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies.
The study has produced a sophisticated and…
Continue Reading
-
Author Correction: Beta activity in human anterior cingulate cortex mediates reward biases
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
Continue Reading
-
Engrafted nitrergic neurons derived from hPSCs improve gut dysmotility in mice
Culture and maintenance of undifferentiated human stem cells
The hESC line H9 (WA09-WiCell, RRID:CVCL_9773), along with its reporter-expressing derivatives (hSYN-ChR2–eYFP and NOS1-GFP), and the induced PSC line WTC-11 (UCSFi001-A,…
Continue Reading