A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders. These essential enzymes, known for maintaining RNA metabolism, are revealed as central players in a…
Category: 5. Biology
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Parse Biosciences GigaLab to support Mount Sinai researchers in generating one of the largest Alzheimer’s and Parkinson’s single cell datasets
Parse Biosciences today announced their commitment to support researchers from the Icahn School of Medicine at Mount Sinai in generating one of the largest single cell datasets focused on understanding alternative splicing events in…
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Revolutionary “Material Maze” Could Prevent Bacterial Infections
Scientists used patterned plastic surfaces to trick bacteria into halting their own spread. These designs may prevent infections without the need for antimicrobial drugs. Scientists at the University of Nottingham have identified surface patterns…
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Young green quinoa as a sustainable functional crop with anti-inflammatory effects in macrophage cells
Given the rising prevalence of NCDs associated with chronic inflammation, integrating young green quinoa (YGQ) extracts into dietary products could contribute to mitigating inflammation-related health conditions, such as cardiovascular disease,…
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Multi-omic analysis of gallbladder cancer identifies distinct tumor microenvironments associated with disease progression
Roa, J. C. et al. Gallbladder cancer. Nat. Rev. Dis. Prim. 8, 69 (2022).
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Valle, J. W., Kelley, R. K., Nervi, B., Oh, D.-Y. & Zhu, A. X. Biliary tract cancer. Lancet…
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Doublet decoding of tRNASer3 demonstrates plasticity of ribosomal decoding center
Components
E. coli 70S ribosomes were purified from E. coli MRE600 cells according to21, including two steps of pelleting through a 1.1 M sucrose cushion and rate-zonal centrifugation in a preformed 10−40 % sucrose gradient. ASLs and mRNAs…
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Author Correction: Modular RNA motifs for orthogonal phase separated compartments
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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CryoDRGN-AI: neural ab initio reconstruction of challenging cryo-EM and cryo-ET datasets
Nakane, T. et al. Single-particle cryo-EM at atomic resolution. Nature 587, 152–156 (2020).
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Yip, K. M., Fischer, N., Paknia, E.,…
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A trial of fetal cells for Parkinson’s disease brings lessons for the field
A trial of fetal cells for Parkinson’s disease brings lessons for the field
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