Expanding stem-like cells revealed from a PDX model of a relapsing T-ALL patient
To investigate differences in the individual cellular architecture of T-ALL during disease progression, we first conducted VASA-seq on initial and relapse-derived…
Category: 5. Biology
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Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis
Following the publication of this article, the authors noted that the KYSE410 USP2 image in Figure 5E was mistakenly duplicated with the KYSE150 shNC image in Figure 5E. Additionally, the KYSE150…
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PARP inhibitor-induced anti-tumour chemokine response is suppressed by dipeptidyl peptidase 4 (DPP4) in ovarian cancer
Mirza MR, Coleman RL, González-Martín A, Moore KN, Colombo N, Ray-Coquard I, et al. The forefront of ovarian cancer therapy: update on PARP inhibitors. Ann Oncol. 2020;31:1148–59.
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How and when organisms edit their own genomes
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Charting human hematopoiesis to understand B cell leukemia
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Innate immunity drives epithelial cell plasticity during prostate tumor formation
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This is a summary of: Jiang, C. et al. Innate immunity and the NF-κB pathway control prostate stem cell…
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Circular RNA circIGF1R controls cardiac fibroblast proliferation through regulation of carbohydrate metabolism
Identification of circIGF1R in heart failure tissue and validation of its circular conformation
Global RNA sequencing was performed using left ventricular cardiac tissue from HF patients (in comparison to that of healthy controls) to evaluate the…
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Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features
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Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH
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Mouse radial spoke 3 is a metabolic and regulatory hub in cilia
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Fliegauf, M., Benzing, T. & Omran, H. When cilia go bad: cilia…
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