Category: 5. Biology

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  • A metabolic hub in ciliary and flagellar motion

    A metabolic hub in ciliary and flagellar motion

    A metabolic hub in ciliary and flagellar motion

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  • Role of stem-like cells in chemotherapy resistance and relapse in pediatric T-cell acute lymphoblastic leukemia

    Role of stem-like cells in chemotherapy resistance and relapse in pediatric T-cell acute lymphoblastic leukemia

    Expanding stem-like cells revealed from a PDX model of a relapsing T-ALL patient

    To investigate differences in the individual cellular architecture of T-ALL during disease progression, we first conducted VASA-seq on initial and relapse-derived…

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  • Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis

    Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis

    Following the publication of this article, the authors noted that the KYSE410 USP2 image in Figure 5E was mistakenly duplicated with the KYSE150 shNC image in Figure 5E. Additionally, the KYSE150…

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  • PARP inhibitor-induced anti-tumour chemokine response is suppressed by dipeptidyl peptidase 4 (DPP4) in ovarian cancer

    PARP inhibitor-induced anti-tumour chemokine response is suppressed by dipeptidyl peptidase 4 (DPP4) in ovarian cancer

  • Mirza MR, Coleman RL, González-Martín A, Moore KN, Colombo N, Ray-Coquard I, et al. The forefront of ovarian cancer therapy: update on PARP inhibitors. Ann Oncol. 2020;31:1148–59.

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  • How and when organisms edit their own genomes

    How and when organisms edit their own genomes

  • Lindahl, T. Instability and decay of the primary structure of DNA. Nature 362, 709–715 (1993).

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  • An, R. et al. Non-enzymatic depurination of nucleic acids:…

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  • Charting human hematopoiesis to understand B cell leukemia

    Charting human hematopoiesis to understand B cell leukemia

  • Gökbuget, N. et al. Blood 143, 1903–1930 (2024).

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  • Paietta, E. et al. Blood 138, 948–958 (2021).

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  • Innate immunity drives epithelial cell plasticity during prostate tumor formation

    Innate immunity drives epithelial cell plasticity during prostate tumor formation

    Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

    This is a summary of: Jiang, C. et al. Innate immunity and the NF-κB pathway control prostate stem cell…

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  • Circular RNA circIGF1R controls cardiac fibroblast proliferation through regulation of carbohydrate metabolism

    Circular RNA circIGF1R controls cardiac fibroblast proliferation through regulation of carbohydrate metabolism

    Identification of circIGF1R in heart failure tissue and validation of its circular conformation

    Global RNA sequencing was performed using left ventricular cardiac tissue from HF patients (in comparison to that of healthy controls) to evaluate the…

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  • Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features

    Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features

  • Arber, D. A. et al. International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data. Blood 140, 1200–1228 (2022).

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