The gut microbiome has been associated with many heath conditions, and scientists are exploring the links between the gut microbiome and Parkinson’s disease, a neurodegenerative disease associated with aging….
Category: 5. Biology
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Scientists reveal a spontaneous reaction that could have started life
Urea is one of the most important industrial chemicals produced worldwide. It is used as a fertiliser, for the production of synthetic resins and explosives and as a fuel additive for cleaning car exhaust gases. Urea is also believed to be a…
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Discovery of a genetic dimmer switch controlling embryonic development
A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that controls how genes are switched ‘on’ and ‘off’ during embryonic development. Published today in…
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Expanding the genetic code in mammalian cells using pseudouridine modified codons
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of Chemistry and Molecular…
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Global effort enters an active growth phase to preserve the Earth’s microbial heritage
A global effort to create a “microbial Noah’s Ark” to preserve the world’s diverse collection of healthy microbes before they disappear is now entering an active growth phase.
In a perspective article published in Nature…
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Proteome imbalance from aneuploidy linked to mitochondrial dysfunction
It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances. Surprisingly, they found that…
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Integrated multi-omics analyses of synaptosomes revealed synapse-associated novel targets in Alzheimer’s disease
Post-mortem brain samples
Post-mortem brains from AD patients and unaffected controls were obtained from NIH NeuroBioBanks- [1] Human Brain and Spinal Fluid Resource Center, 11301 Wilshire Blvd (127 A), Los Angeles, CA. [2] Brain Endowment Bank,…
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Explainable, federated deep learning model predicts disease progression risk of cutaneous squamous cell carcinoma
Patient cohorts
For the initial training cohort, all patients with a primary cSCC diagnosed and treated by excision at the Department of Dermatology at the University Hospital Cologne (Cologne cohort) between January 2009 to May 2019 were…
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Author Correction: The AI drug revolution needs a revolution
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…
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Author Correction: Distinct virome compositions and lack of viral diversification indicate that viral spillover is a dead-end between the western honey bee and the common eastern bumblebee
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…
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