Category: 5. Biology

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  • TUFT1 stabilizes TGF-β receptor II protein and facilitates activation of hepatic stellate cells into metastasis-promoting myofibroblasts

    TUFT1 stabilizes TGF-β receptor II protein and facilitates activation of hepatic stellate cells into metastasis-promoting myofibroblasts

    Mass spectrometry identified TUFT1 as a TβRII-binding protein in primary human HSCs

    To identify proteins that interacted with TβRⅡ, we generated TβRⅡ-HA-overexpressing HSCs by transducing primary human HSCs with lentiviruses encoding…

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  • Mitoxantrone alters CD24/Siglec-10 expression in malignant brain tumor models

    Mitoxantrone alters CD24/Siglec-10 expression in malignant brain tumor models

    CD24 is associated with genes predicting prognosis in brain tumors

    Understanding CD24-tumor heterogeneity is crucial for effective biomarker targeting. We first investigated the association of CD24 with a 10-gene…

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  • Deep learning based individual identification and population estimation of the yellow spotted mountain newt (Neurergus derjugini)

  • Karczmarski, L., Chan, S. C. Y., Chui, S. Y. S. & Cameron, E. Z. Individual identification and photographic techniques in mammalian ecological and behavioural research—Part 2: field studies and applications. Mamm. Biol. 102, 1047–1054 (2022).

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  • The morpho-kinetic landscape of macrophage modes during wound healing in zebrafish

  • Sonnemann, K. J. & Bement, W. M. Wound repair: toward understanding and integration of single-cell and multicellular wound responses. Ann. Rev. Cell Develop. Biol. 27, 237–263 (2011).

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  • Wynn,…

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  • Thyroid cancer detection and classification using spectral imaging and artificial intelligence

  • Siegel, R. L., Giaquinto, A. N. & Jemal, A. Cancer statistics, 2024. CA Cancer J. Clin. 74, 12–49 (2024).

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  • LiVolsi, V. A. Papillary thyroid carcinoma: an update. Mod. Pathol. 24, S1–S9…

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  • Genome wide data recover hierarchical genetic structure and help define conservation units for the threatened Asian Houbara

    Genome wide data recover hierarchical genetic structure and help define conservation units for the threatened Asian Houbara

  • Allendorf, F. W., Luikart, G. & Aitken, S. N. Conservation and the Genetics of Populations. 2nd ed. i-xviii, 1–602 (2013).

  • Ryder, O. A. Species conservation and systematics—The dilemma of subspecies. Trends Ecol. Evol. 1(1), 9–10 (1986).

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  • Scientists develop technique to identify malfunctions in our genetic code

    Scientists develop technique to identify malfunctions in our genetic code

    An international team of researchers including scientists from The Australian National University (ANU) have developed a way to reveal the smallest of malfunctions in the biochemical machinery that makes proteins in our bodies. According to the…

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  • A peek inside the clockwork that drives embryonic body patterning

    A peek inside the clockwork that drives embryonic body patterning

    The architecture of the body is not encoded as a formal blueprint; rather, it’s the tightly orchestrated activation and deactivation of genes that coordinate body development. Many of these processes are not fully understood, but RIKEN…

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  • Data-driven 3D chromosome model reveals structural and dynamic features of DNA

    Data-driven 3D chromosome model reveals structural and dynamic features of DNA

    Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t used as often. Understanding the complexity…

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