Nikkhah, M., Rezazadeh, M., Khorshid, K., Biglarian, H. R., Ohadi, M. & A. & An exceptionally long CA-repeat in the core promoter of SCGB2B2 links with the evolution of apes and old world monkeys. Gene 576, 109–114.
Category: 5. Biology
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Repurposing FDA approved drugs for psoriasis indications through integrated molecular docking, one-SVM algorithm, and molecular dynamics simulation approaches
Data retrieval
A systematic literature search identified; 19 autoimmune disorders, 5 cardiovascular risk factors, 2 inflammatory conditions and a mood disorder closely aligned to psoriasis (Table 1). The FDA approved drugs were explored using…
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Chemotherapy treatment alters DNA methylation patterns in the prefrontal cortex of female rat brain
In the past, our lab had established that AC-chemotherapy administration can cause decline in spatial memory in both ovariectomized and intact female Sprague-Dawley rats using behavioral assays15. We have also shown that it activates stress…
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Rapid detection of antibiotic resistance in Burkholderia pseudomallei using MALDI-TOF mass spectrometry
Melioidosis remains a critical public health concern due to its high mortality rate, particularly when delays or inappropriate antibiotic treatments occur, increasing the risk of death within 48 h of symptom onset12,13. In this study, the…
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Tumour cells mimic erythroblasts to hijack iron from bone marrow macrophages
Bone is a highly specialized organ that supports haematopoiesis but can also serve as a metastatic niche for tumour cells. Metastatic cells must overcome the hypoxic, nutrient-limited conditions in the bone marrow to establish secondary growth….
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Rice QTL hotspots related with seed grain size, shape, weight, and color based on genome wide association study and linkage mapping
Seed grain characteristics in local rice accessions and RILs population
In our experiment, we assessed the phenotypic traits of Indonesian local rice accessions, focusing on size (area, perimeter, width, length-to-width ratio), shape (circularity,…
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Study of caspase-6 activity in aggressive HCT116 cells using methotrexate-encapsulated lactoferrin-conjugated solid lipid nanoparticles via in silico and in vitro approaches
Methotrexate binding affinities and interactions
Methotrexate has shown different affinities towards the target proteins; however, the highest interaction was seen with Caspase-6 (PDB ID: 3OD5), which has a docking score of −9.316 and Glide…
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Repulsion in the human hippocampus is linked to internal beliefs
Repulsion refers to the phenomenon of highly similar events generating patterns of hippocampal activity that are (counterintuitively) less similar to each other than are those generated by unrelated events. Although observable in human…
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Reproductive timing and intensity in a Galápagos intertidal mollusc are modulated by thermal phases
Anderson, S. C., Flemming, J. M., Watson, R. & Lotze, H. K. Rapid global expansion of invertebrate fisheries: Trends, drivers, and ecosystem effects. PLoS ONE 6, e14735 (2011).
Google…
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Identification of the ACA/ECA gene family and preliminary verification of their functional in calcium transport in lettuce
Information on ACA/ECA gene family members and phylogenetic relationships in lettuce
This study identified 18 members of the lettuce ACA/ECA family using bioinformatics methods. The ACA/ECA protein family can be categorized into four highly…
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