Oncolytic virus upregulates IL-18 receptor expression in the TME
Our previous study demonstrated that the M1 virus effectively suppresses murine melanoma B16F10 in vivo and shapes the TME into an inflammatory state; however, its antitumor effect is…
Category: 5. Biology
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Context-Seq: CRISPR-Cas9 targeted nanopore sequencing for transmission dynamics of antimicrobial resistance
Murray, C. J. et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet 399, 629–655 (2022).
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Fuhrmeister, E. R. et al….
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A functional neuroimaging biomarker of mild cognitive impairment using TD-fNIRS
General description
The two participant groups, MCI and age-matched HC (Table 1) wore the Kernel Flow2 TD-fNIRS headset and their neurophysiological data was measured while they performed cognitive tasks: Verbal Fluency and N-Back working memory…
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Assembly mechanism of the snRNA nuclear export complex
Assembly mechanism of the snRNA nuclear export complex
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Halomonas sp. MC140, a polyhydroxyalkanoate (PHA) producer isolated from the Arctic environment
Rehm, B. H. Bacterial polymers: Biosynthesis, modifications and applications. Nat. Rev. Microbiol. 8, 578–592. https://doi.org/10.1038/nrmicro2354 (2010).
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Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features
Human samples
Healthy human blood (collected in EDTA anticoagulant-containing tubes) was purchased anonymously from the French blood agency (Etablissement Français du sang, Lyon France, convention 16-093). Participants were French voluntary…
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Characteristics of the integration sites and module structures of the Tn916 and its family
Localization, classification and naming of Tn916 and other members of this family in bacterial genomes
A total of 577 Tn916 family transposons were identified, and by using AAB60030.1 as a benchmark, they were found to be integrated into 240…
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Decoding 3D cell morphology with interpretable point cloud models
Vasan, R. et al. Nat. Methods https://doi.org/10.1038/s41592-025-02729-9 (2025).
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Stringer, C., Wang, T., Michaelos, M. & Pachitariu, M. Nat. Methods 18, 100–106 (2021).
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Discovering molecular signatures in kidney transplant biopsies with borderline changes and isolated V-lesions: single-cell RNA-sequencing analysis of human blood and tissue Spatial transcriptomics
Study population and clinical data collection
This study was approved by the Institutional Review Board (IRB) of the Seoul National University Hospital (IRB # 2205-175-1329). The study adhered to the ethical guidelines of the Declaration of…
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Comprehensive analysis of PIK3CA mutations in advanced colorectal cancer using circulating tumor DNA profiling
Siegel, R. L., Wagle, N. S., Cercek, A., Smith, R. A. & Jemal, A. Colorectal cancer statistics, 2023. Cancer J. Clin. 73, 233–254 (2023).
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Biller, L. H. & Schrag, D. Diagnosis…
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