Category: 5. Biology

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  • Intranasal monoclonal antibodies do not prevent respiratory infection in a randomized, controlled experimental infection trial

    Intranasal monoclonal antibodies do not prevent respiratory infection in a randomized, controlled experimental infection trial

    Study design and participants

    We conducted a single-center, randomized, placebo-controlled, double-blind human infection study in the Netherlands between October and December 2023 (EudraCT number 2020-004137-21). Individuals responding to local…

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  • Returning home: fostering growth of Brazilian research

    Returning home: fostering growth of Brazilian research

    Returning home: fostering growth of Brazilian research

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  • Phylogenetically informed predictions outperform predictive equations in real and simulated data

    Phylogenetically informed predictions outperform predictive equations in real and simulated data

    Simulations

    The performance of phylogenetically informed prediction on ultrametric trees

    Here, we assess the performance of phylogenetically informed predictions compared to OLS and PGLS-derived predictive equations under different evolutionary…

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  • The intracellular bacterium Orientia tsutsugamushi uses the autotransporter ScaC to activate BICD adaptors for dynein-based motility

    The intracellular bacterium Orientia tsutsugamushi uses the autotransporter ScaC to activate BICD adaptors for dynein-based motility

    Constructs and plasmids

    The full-length mouse BICD2 sequence (UniProt Q921C5) was codon optimized for expression in Sf9 insect cells (Epoch Life Sciences) and cloned into a pACEBac1 vector encoding a N-terminal Strep-tag followed a PreScission…

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  • Machine learning-based identification of wastewater treatment plant-specific microbial indicators using 16S rRNA gene sequencing

    Machine learning-based identification of wastewater treatment plant-specific microbial indicators using 16S rRNA gene sequencing

  • Cai, L., Ju, F. & Zhang, T. Tracking human sewage microbiome in a municipal wastewater treatment plant. Appl. Microbiol. Biotechnol. 98(7), 3317–3326 (2014).

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  • Lee, S….

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  • VISTA is a potential target for immunotherapy in B-cell acute lymphoblastic leukemia in children

    VISTA is a potential target for immunotherapy in B-cell acute lymphoblastic leukemia in children

  • Malard, F. & Mohty, M. Acute lymphoblastic leukaemia. Lancet 395, 1146–1162. https://doi.org/10.1016/S0140-6736(19)33018-1 (2020).

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  • Pulte, D., Gondos, A. &…

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  • Taylor’s law predicts unprecedented pulses of forest disturbance under global change

    Taylor’s law predicts unprecedented pulses of forest disturbance under global change

  • Turner, M. G. Disturbance and landscape dynamics in a changing world. Ecology 91, 2833–2849 (2010).

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  • Thom, D. & Seidl, R. Natural disturbance impacts on ecosystem…

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  • A single main-chain hydrogen bond required to keep GABAA receptors closed

    A single main-chain hydrogen bond required to keep GABAA receptors closed

  • Infield, D. T., Schene, M. E., Galpin, J. D. & Ahern, C. A. Genetic code expansion for mechanistic studies in ion channels: an (un)natural union of chemistry and biology. Chem. Rev. 124, 11523–11543 (2024).

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  • Composition of the freshwater decapod crustacean communities in an area of mining in Brazilian Amazonia and the variation related to environmental parameters

    Composition of the freshwater decapod crustacean communities in an area of mining in Brazilian Amazonia and the variation related to environmental parameters

  • Ye, H., Zeng, C., Tsutsui, N. & Dircksen, H. Editorial: Crustacean reproductive physiology and its applications. Front. Physiol. 13, 85 (2022).

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  • Wacker, A. & Harzsch, S….

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