Category: 5. Biology

Continue Reading

  • A p53-controlled lysosomal recycling circuit fuels phospholipid synthesis

    A p53-controlled lysosomal recycling circuit fuels phospholipid synthesis

    Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

    This is a summary of: Yashinskie, J. J. et al. p53 increases phospholipid headgroup scavenging in senescence….

    Continue Reading

  • AI-driven virtual screening platform identifies novel NSUN2 inhibitor candidates for targeted cancer therapy: a computational drug discovery approach

  • Blanco, S. et al. Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J. 33, 2020–2039 (2014).

    Google Scholar 

  • Frye, M., Harada, B. T., Behm, M. & He, C. RNA…

  • Continue Reading

  • Reduced expression of BIRC2 and BIRC3 associated with longer survival in pediatric high-grade gliomas

  • Ostrom, Q. T. et al. Alex’s lemonade stand foundation infant and childhood primary brain and central nervous system tumors diagnosed in the united States in 2007–2011. Neuro Oncol. 16 (Suppl 10), x1–x36.

  • Continue Reading

  • Mechanistic insights into PABPC5-mediated regulation of apoptosis in glioma pathophysiology

  • Ostrom, Q. T. et al. Statistical report: primary brain and other central nervous system tumors diagnosed in the united States in 2014–2018. Neuro Oncol. 23, iii1–iii105 (2021).

    Google Scholar 

  • Louis, D. N….

  • Continue Reading

  • Association-induced folding governs surrogate light chain and pre-B cell receptor core assembly

    Association-induced folding governs surrogate light chain and pre-B cell receptor core assembly

    Molecular biology and recombinant expression of the SLC proteins and antibody domains

    Constructs for λ5 and VpreB variants were synthesized by GeneArt (Regensburg, Germany) and cloned into the pE-SUMOpro vector (KanR) (Lifesensors, Malvern, USA)…

    Continue Reading

  • Evolutionary shift in flower shape linked to bird pollinators

    Evolutionary shift in flower shape linked to bird pollinators

    How do plants evolve into new species to accommodate other species? This is what a recent study published in New Phytologist hopes to address as a team of scientists investigated longstanding models discussing…

    Continue Reading

  • How fire-loving fungi learned to eat charcoal

    How fire-loving fungi learned to eat charcoal

    Wildfire causes most living things to flee or die, but some fungi thrive afterward, even feasting on charred remains. New University of California, Riverside research finds the secret to post-fire flourishing hidden in their genes. The study is…

    Continue Reading

  • Real-time imaging captures contact between cells and between a single neuron's extensions

    Real-time imaging captures contact between cells and between a single neuron's extensions

    Living organisms are made up of hundreds of thousands of cells that cooperate to create the organs and systems that breathe, eat, move, and think. Now, researchers from Japan have developed a new way to track how and when cells touch each other…

    Continue Reading

  • Bacterial 'brains' operate on the brink of order and disorder

    Bacterial 'brains' operate on the brink of order and disorder

    The sensory proteins that control the motion of bacteria constantly fluctuate. AMOLF researchers, together with international collaborators from ETH Zurich and University of Utah, found out that these proteins can jointly switch on and off at the…

    Continue Reading