Category: 5. Biology

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  • Natural variation of AcEGY3 mediates chloroplastic ROS homeostasis to confer kiwifruit thermotolerance

    Natural variation of AcEGY3 mediates chloroplastic ROS homeostasis to confer kiwifruit thermotolerance

  • Zuo, L. L., Wang, Z. Y., Fan, Z. L., Tian, S. Q. & Liu, J. R. Evaluation of antioxidant and antiproliferative properties of three Actinidia (Actinidia kolomikta, Actinidia arguta, Actinidia chinensis) extracts in vitro. Int. J. Mol. Sci. 13,…

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  • MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures

    MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures

    Architecture and performance of MIC

    The MIC tool assigns labels to waters and ions modeled in PDB structures, identified from spherical features in cryo-EM and x-ray crystallography maps. The overall workflow consists of three steps: (1)…

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  • The length of time series affects patterns of species synchrony

    The length of time series affects patterns of species synchrony

    Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

    This is a summary of: Luo, M. et al. Short time series obscure compensatory dynamics in ecological…

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  • Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria

    Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria

    Bioprospecting Desulfobacterota genomes for interesting ssOST candidates

    The current armamentarium of characterized bacterial ssOSTs is insufficient for glycoprotein engineering applications that endeavor to recapitulate human-type glycosylation…

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  • Dimerization and substrate recognition of human taurine transporter

    Dimerization and substrate recognition of human taurine transporter

    Dimerization of TauT

    To explore the molecule basis of substrate recognition mechanism by TauT, we expressed the full-length and wild-type (WT) human TauT in HEK293S N-acetyl-glucosaminyltransferase I (GnTI) cells and performed the [3H]-taurine…

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  • MultiFG: integrating molecular fingerprints and graph embeddings via attention mechanisms for robust drug side effect prediction

    MultiFG: integrating molecular fingerprints and graph embeddings via attention mechanisms for robust drug side effect prediction

    Dataset

    We developed our model based on the dataset organized by Galeano et al.18, which includes 759 drugs and 994 side effects. The frequencies information of drug side effect pairs is mapped to five levels: very rare (1), rare (2), infrequent…

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  • Coral-like branching of conjunctival intracorneal neoplasia: a 40-day progression

    Coral-like branching of conjunctival intracorneal neoplasia: a 40-day progression

    Coral-like branching of conjunctival intracorneal neoplasia: a 40-day progression

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  • Kitlo hematopoietic stem cells exhibit distinct lymphoid-primed chromatin landscapes that enhance thymic reconstitution

    Kitlo hematopoietic stem cells exhibit distinct lymphoid-primed chromatin landscapes that enhance thymic reconstitution

    Animal use

    Young female mice (6–10 weeks of age): C57BL/6J (CD45.2/H-2Kb, JAX#000664), B6.SJL-PtprcaPepcb/BoyJ (CD45.1, JAX# 002014), and B6(C)-Gt (ROSA)26Sorem1.1(CAGcas9*EGFP) Rsky/J (Rosa26Cas9 KI, JAX#028555) mice were purchased from…

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  • Poltergeist-Like 2 (PLL2)-dependent activation of herbivore defence distinguishes systemin from other immune signalling pathways

    Poltergeist-Like 2 (PLL2)-dependent activation of herbivore defence distinguishes systemin from other immune signalling pathways

    Plant material and growth conditions

    Tomato (Solanum lycopersicum cv. UC82B) and N. benthamiana plants were cultivated in growth cabinets at 26 °C, with 16 h photoperiod, 100 µmol m−2 s−1 light intensity and 75% relative humidity….

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