Living organisms are made up of hundreds of thousands of cells that cooperate to create the organs and systems that breathe, eat, move, and think. Now, researchers from Japan have developed a new way to track how and when cells…
Category: 5. Biology
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Characterising nanobody developability to improve therapeutic design using the Therapeutic Nanobody Profiler
Jain, T. et al. Biophysical properties of the clinical-stage antibody landscape. Proc. Natl. Acad. Sci. USA 114, 944–949 (2017).
Raybould, M. I. J. et al. Five computational developability…
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Deep learning framework for timely detection and classification of chili leaf diseases and pests
Kanaparthi Kantharaju, S. et al. Deep Learning Methods for Detecting Chilli Pests: A Novel Performance Analysis. https://doi.org/10.12912/27197050/187071. (2024). https://doi.org/10.12912/27197050/187071
Pengyan Su, H. et al. Improvement of the…
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Reliable repurposing of the antibody interactome inside the cell
Kovaltsuk, A. et al. Observed antibody space: a resource for data mining next-generation sequencing of antibody repertoires. J. Immunol. 201, 2502–2509 (2018).
Abanades, B. et al. The Patent…
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Radiosensitizing effects of silver nanoparticles targeting angiogenesis and matrix metalloproteinase signaling in triple negative breast cancer cell lines
Santucci, C. et al. Progress in cancer mortality, incidence, and survival: a global overview. Eur. J. Cancer Prev. 29, 367–381 (2020).
Maman, S. & Witz, I. P. A history of exploring cancer in…
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Repurposing nuclear receptors for ligand-responsive liquid condensate formation and gene regulation
Bashor, C. J., Hilton, I. B., Bandukwala, H., Smith, D. M. & Veiseh, O. Engineering the next generation of cell-based therapeutics. Nat. Rev. Drug Discov. 21, 655–675 (2022).
Brayshaw, L. L. et al. The role of small molecules in cell and gene…
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Rhizosphere microbial functions drive ecological stoichiometry in soils across an elevational gradient of a temperate mountain ecosystem
Yang, R. et al. Nitrogen inhibitors improve soil ecosystem multifunctionality by enhancing soil quality and alleviating microbial nitrogen limitation. Sci. Total Environ. 880, 163238 (2023).
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BCL-xL as a therapeutic target in cetuximab-refractory colorectal cancer
Biller LH, Schrag D. A Review of the Diagnosis and Treatment of Metastatic Colorectal Cancer-Reply. JAMA. 2021;325:2405.
van Emburgh BO, Sartore-Bianchi A, Di Nicolantonio F, Siena S, Bardelli A….
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Discover the maze-like network for glabridin biosynthesis
Dvora, H. & Koffas, M. Microbial Production of Food Ingredients, Enzymes and Nutraceuticals, 234–261 (Elsevier, 2013).
Walsh, C. T. Tailoring enzyme strategies and functional groups in biosynthetic pathways. Nat. Prod. Rep. 40, 326–386 (2023).
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The expression profiling of serum circPHLPP2 and LncRNA ILF3 in colorectal cancer patients
Morgan, E. et al. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut 72, 338–344 (2023).
Awedew, A. F., Asefa, Z. & Belay, W. B. Burden…
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