Neuroblastoma is one of the most common solid tumors in children, with a higher incidence in children under the age of 2 (approximately 8–10% of all pediatric cancers)1,2. Although modern treatment strategies have significantly improved the…
Category: 5. Biology
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Rosmarinic acid potentiates gefitinib in lung adenocarcinoma by modulating interactions between cancer cells and cancer-associated fibroblasts
NSCLC-fibroblast interaction promotes epithelial-mesenchymal transition
To identify the optimal cell model for investigating tumor-stromal interactions, we first compared miR-21 expression profiles across multiple NSCLC cell lines, including both…
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Scientists Stunned As Tomatoes “De-Evolve” in the Galapagos
New research uncovers reversal of evolution in island plants. On the younger, volcanic islands of the Galápagos, wild tomato plants are exhibiting an unusual behavior. They appear to be discarding millions of years of evolutionary changes and…
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Alien Fish Species Discovered in the Philippines’ Largest Lake
Ateneo biologists have confirmed the presence of the invasive tinfoil barb (Barbonymus schwanefeldii) in Laguna de Bay, raising concerns that the species could disrupt native fish populations and damage the lake’s delicate ecosystem. A…
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Common Farm Chemical Is Accelerating the Insect Apocalypse
Insects exposed to low levels of chlorothalonil suffer major reproductive harm. Its continued use threatens pollination and ecosystem balance. New research from Macquarie University has revealed that a commonly applied agricultural chemical, used…
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Ireland’s first and only BioBrillouin microscope installed at Trinity College Dublin
Trinity College Dublin now has Ireland’s first and only BioBrillouin microscope, which will enable researchers to make giant strides in the fields of inflammation, cancer, developmental biology and biomedical materials, among…
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Corneal safety assessment of germicidal far UV-C radiation
Reconstructed human cornea epithelium (RHCE)
The first studies of UV-induced DNA damage were carried out using RHCE. RHCE were used to study both the immediate and 24 h post-irradiation effects, as well as the effects of repeated exposures. The…
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The role of sodium pyruvate in mitigating the cytotoxic effects of vanadium on CHO-K1 cells
Reagents
Dulbecco’s modified Eagle’s medium Hams F-12 (DMEM)/F12 1:1 (cat. No. D8437), fetal bovine serum (FBS, Cat No. F9665), bovine calf serum (CS, Cat No. 12138 C), L-glutamine solution (Cat No. G7513), antibiotic antimycotic solution…
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Author Correction: Glacier-fed lakes produce lower methane fluxes than non-glacier-fed lakes on the Tibetan Plateau
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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TTK activates ATR through RPA2 phosphorylation to promote olaparib resistance in ovarian cancer
Cell lines and cell culture
OVCAR8 cells were obtained from the M.D. Anderson Cancer Center’s Characterized Cell Line Core. OV90 and UWB1.289 cells were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA), while…
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