NAs and pegylated interferon (Peg-IFN) are currently used for the treatment of CHB. However, the achievement rate of HBsAg clearance, the long-term goal of treatment, is very low. Such current conditions have prompted the development of…
Category: 5. Biology
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Selenium protected NMRI mice against methotrexate induced testicular injury
Heidari, R., Assadollahi, V., Marashi, S. N., Elahian, F. & Mirzaei, S. A. Identification of novel LncRNAs related to colorectal Cancer through bioinformatics analysis. Biomed. Res. Int. 2025 (1), 5538575 (2025).
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A transformer-based architecture for collaborative filtering modeling in personalized recommender systems
The main aim of this research is to conduct a systematic design and performance evaluation of a CF based movie recommendation system using the latest deep learning-based transformers. The framework of this work is divided into several consecutive…
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Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases
Cell culture and reagents
U2OS (ATCC) (RRID: CVCL_0042), RKO (ATCC), HeLa (ATCC), H1299 (ATCC), A549 (ATCC), PANC1 (ATCC), and PEO1 (gift from Francis Crick Institute, Baltimore, London, UK) were grown in Dulbecco’s modified Eagle’s medium…
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Structural snapshots show the roles of TEF30 in repairing the broken photosystem II
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Wang, Y. et al. Roles of multiple TEF30-associated intermediate complexes in the repair…
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In silico investigation of ketamine and methylphenidate drug-drug conjugate for MDD and ADHD treatment using MD simulations and MMGBSA
Collins, P. Y. et al. Grand challenges in global mental health. Nature 475, 27–30 (2011).
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Depression, W. Other common mental…
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Peripheral immune imbalance in pediatric fulminant myocarditis revealed by single-cell sequencing and plasma proteomics
Schultheiss HP, Kühl U, Cooper LT. The management of myocarditis. Eur Heart J 2011;32:2616–25.
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Law YM, Lal AK, Chen S, Čiháková D, Cooper LT Jr, Deshpande S, et al….
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A molecular decoy for phage defence
First discovered in retroviruses, reverse transcriptases are enzymes that synthesize cDNA from an RNA template molecule. Subsequently, various classes of bacterial reverse transcriptases have been discovered with a role in antiviral defence,…
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AVJ16 inhibits lung carcinoma by targeting IGF2BP1
Tissue culture
H1299 cells were maintained in RPMI medium, and LKR-M and RKO cells were maintained in DMEM (Biological Industries – Israel). Both media contained 10% FCS (Biological Industries) and 10 μg/mL ciprofloxacin (Bayer). For all the…
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Annual gonadal cycle of the invasive catfish brown bullhead Ameiurus nebulosus from an oxbow lake of vistula river, Poland
Welcomme, R. L. International introductions of inland aquatic species. FAO Fisheries Tech. Papers. 294, 1–318 (1988).
Elvira, B. First records of the North American catfish Ictalurus melas…
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