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Category: 5. Biology
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NOX4 serves as a pan-cancer prognostic biomarker and therapeutic target in tumorigenesis
NOX4 expression in pan-cancer
This study systematically analyzed the expression characteristics of NOX4 in pan-cancer based on the TCGA-GTEx database. The results revealed significant NOX4 expression differences in various tumor tissues….
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Monitoring of antibodies against SARS-CoV-2 over 2 years and characterization of immune responses following Omicron infection in a South Indian community cohort
Seropositive unvaccinated individuals exhibited higher antibody levels and a higher ACE2 Inhibition percentage
Among the 211 unvaccinated individuals during the 2-year follow-up, 170 were previously exposed (SP) and 41 were unexposed (SN) at…
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Glioblastoma at the crossroads: current understanding and future therapeutic horizons
Ostrom, Q. T. et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013-2017. Neuro Oncol. 22, iv1–iv96 (2020).
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Development and validation of a predictive nomogram for postoperative upper limb lymphedema in breast cancer patients: a retrospective cohort study
In this study, we identified several key factors associated with the risk of developing postoperative upper limb lymphedema (PULL) in breast cancer patients. Our findings revealed that older age, higher BMI, advanced TNM stage, hypertension, and…
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Author Correction: Sarbecovirus RBD indels and specific residues dictating multi-species ACE2 adaptiveness
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…
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Replay and representation dynamics in the hippocampus of freely flying bats
Cognitive functions for navigation and memory rely on emergent properties of neural ensembles in the hippocampus, such as activity replay1–5 and theta sequences6–9. Yet, whether and how these phenomena generalize across species with distinct…
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A novel peptide 66CTG stabilizes Myc proto-oncogene protein to promote triple-negative breast cancer growth
Cell lines
The cell lines of HEK293T, MDA-MB-468, Hs578T and MCF7 were cultured in DMEM Medium (Gibco, Cat: C11995500BT) with 10% Fetal bovine serum (FBS, ExCell, Cat: FSD500). The cell lines of HCC1806 and HCC1937 were cultured in RPMI 1640…
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Integrated bioinformatics and experimental analysis of mitochondrial-associated membrane function and mechanism in acute respiratory distress syndrome
Differentially expressed genes related to ARDS
By comparing ARDS samples with control groups, a total of 3152 differentially expressed genes (DEGs) were identified, showing significant differences between the two groups (corrected p < 0.05,…
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Quantifying the intra- and inter-species community interactions in microbiomes by dynamic covariance mapping
Dynamic covariance mapping (DCM)
Theory
We first provide a formal introduction to the ecological and mathematical theory behind DCM and its biological intuition. Without loss of generality, the microbiome as an ecological community can be described…
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