In cancer research, MR mitigates the errors and impacts associated with traditional randomized control trials and alleviates issues with reverse causality and confounding variables12. In medical research, observational studies are susceptible to…
Category: 5. Biology
-
Decoding the heat stress resilience in Chickpea (Cicer arietinum L.): multi-trait analysis for genotypic adaptation
Genetic variation for evaluated traits under non-stress and heat stress environment
There was significant genotypic variation (σ²g) for all phenological (DFF, DF50, DPI, DM) and physiological traits (CHL, FLV, NDVI) (Table 2). Under non-stress…
Continue Reading
-
Multomic analysis reveals the potential of LAG3 as a prognostic and immune biomarker and its validation in osteosarcoma
Expression and mutation
By analyzing the mRNA levels of unpaired and paired samples in the TCGA database, we found that LAG3 expression was increased in breast invasive carcinoma (BRCA), esophageal carcinoma (ESCA), head and neck squamous cell…
Continue Reading
-
Native Lactobacillus and Bifidobacterium probiotics modulate autophagy genes and exert anti-inflammatory effect
Preparation of bacterial strains
To evaluate the beneficial effects of local probiotic strains, we used three Bifidobacterium spp. (i.e., B. bifidum 1001, B. longum 1044, and B. infantis, strains 1015 and 1063) and four Lactobacillus spp. (i.e.,…
Continue Reading
-
Medium-expansion water-based foam depopulation of sheep and goats
Animal subject approval and handling
This study was approved by The Ohio State University’s Institutional Animal Care and Use Committee (#2023A00000050). Inclusion criteria included adult sheep and goats of mixed breeds. Exclusion criteria…
Continue Reading
-
A bridge-like lipid transport protein controls plasma membrane lipid composition and fluidity
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Banerjee, S. et al. The Vps13-like protein BLTP2 regulates phosphatidylethanolamine…
Continue Reading
-
Expanding in situ genome sequencing
Despite recent advances in measuring the transcriptome at cellular resolution, direct approaches to link genome organization to changes in nuclear structure are lacking. Labade et al. expand on a previous in situ genome sequencing approach by…
Continue Reading
-
Decoding the Flavor and Aroma of Cannabis
What compounds are responsible for giving cannabis also called Cannabis sativa L. (C. sativa L.) its unique flavor and smell? This is what a recent study published in Molecules hopes to address as an…
Continue Reading
-
Orange male guppies are hornier
For guppies (Poecilia reticulata) getting ready to mate, the color orange…
Continue Reading
-
Researchers uncover molecular switch controlling DNA packing in cell division
If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the genetic information needs to…
Continue Reading