Psychological stress is widely recognized as an exacerbating factor in atopic dermatitis (AD, also known as eczema), but the precise neuroimmune circuitry that converts emotional strain into skin inflammation has remained unclear. Reporting in…
Category: 5. Biology
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The regulation mechanism of α-linolenic acid bioavailability by flaxseed lignan macromolecules in O/W emulsions
Lai, H. T. et al. D. S., Serial circulating omega 3 polyunsaturated fatty acids and healthy ageing among older adults in the Cardiovascular Health Study: prospective cohort study. BMJ 363, https://doi.org/10.1136/bmj.k4067 (2018).
Lister, N. B. et…
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Disulfide tethering reveals cryptic pockets in oncogenic KRAS
Prior, I. A., Hood, F. E., Hartley, J. L. The frequency of Ras mutations in cancer. Cancer Res. 80, https://doi.org/10.1158/0008-5472.CAN-19-3682.
Wang, H. et al. Annual review of KRAS inhibitors in 2022. Eur. J. Med. Chem. 249.
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Integrated metabolomics analysis of pigment metabolite accumulation and color development of fresh Dendrobium officinale juice after processing
Xu, Z. et al. Pesticide multi-residues in Dendrobium officinale Kimura et Migo: Method validation, residue levels and dietary exposure risk assessment. Food Chem. 343, 128490 (2021).
Xu, L. et…
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Reinvigorating COTL1high NK cells via GITR signalling overcomes immune checkpoint blockade resistance in tsMHC-I-impaired tumours
This study was conducted in full compliance with the applicable ethical guidelines. The HCC specimens were obtained from the First Affiliated Hospital of Nanjing Medical University (JSPH), the Affiliated Wuxi People’s Hospital of Nanjing…
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Evidence of a putative new species Haemagogus ‘Trinidad sp. A’ from the Caribbean sharing mitogenome lineages with species endemic to the Amazon
Arnell, J. & Hal Mosquito studies (Diptera, Culicidae) XXXII. A revision of the genus Haemagogus 10, 1–174.
Alencar, J. et al. Distribution of Haemagogus and Sabethes species in Relation to Forest Cover and Climatic Factors in the Chapada Dos…
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Impacts of drought and manure fertilization on soil and radish resistomes
Effect of treatments on soil ARG relative abundances
Our results indicate that manure application increased the relative abundance of ARGs, in agreement with many previous works60,61,4,16. This increase has been attributed to the (i) transfer of…
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Neuroimmune interferon signals sustain arthritis pain
Basbaum, A. I., Bautista, D. M., Scherrer, G. & Julius, D. Cell 139, 267–284 (2009).
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Pattison, L. A., Krock, E., Svensson, C. I. &…
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Lipid turnover and GEF recruitment collectively determine Rab5 recruitment and activation during the first step of early endosome formation
Schmid, S. L., Sorkin, A. & Zerial, M. Endocytosis: Past, present, and future. Cold Spring Harb. Perspect. Biol. 6, a022509 (2014).
Cullen, P. J. & Steinberg, F. To degrade or not to degrade:…
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Domain gain or loss in a fungal chitinase enables specialization towards antagonism or immune suppression
Seong, K. & Krasileva, K. V. Prediction of effector protein structures from fungal phytopathogens enables evolutionary analyses. Nat. Microbiol. 8, 174–187 (2023).
Bornberg-Bauer, E. & Albà,…
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