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Category: 5. Biology
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Association of gut microbiota and immune gene expression with response to targeted therapy in BRAF mutated melanoma
Previous studies have linked increased alpha diversity and microbial richness in melanoma patients, particularly species from the Firmicutes phylum, with favourable ICI response and adverse effects occurrence7,17,18. In parallel, BRAF- or…
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The effect of exogenous glutathione on meropenem susceptibility in Klebsiella pneumoniae-carbapenemases (KPC)-producing bacteria
Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, et al. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother. 2001;45:1151–61.
Arnold…
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The defensome of prokaryotes in aquifers
The vast reservoir of prokaryotic defensome in groundwater
We established a metagenomic groundwater prokaryotic defensome catalog (GPDC) (see Supplementary Figs. S1, S2 for an overview), encompassing 190,810 defense genes, 90,824 defense systems,…
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The role of exosomes in immunopathology and potential therapeutic implications
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Long-term benefits of TUDCA supplement in ARSACS zebrafish model
Bouhlal, Y., Amouri, R., Euch-Fayeche, E., Hentati, F. & G. & Autosomal recessive spastic ataxia of Charlevoix–Saguenay: An overview. Parkinsonism Relat. Disord. 17, 418–422 (2011).
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APOE deficiency triggers anti-tumour activity of macrophages in liver cancer
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Predicting the potential distribution of Podophyllum hexandrum Royle in the Himalaya under CMIP6 climate projections
Shilky et al. Climate change: A major challenge to biodiversity conservation, ecological services, and sustainable development. in The Palgrave Handbook of Socio-Ecological Resilience in the Face of Climate Change 577–592 (Springer Nature…
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Phase separated condensates of ATRX regulate neural progenitor identity
Human iPSC (hiPSC) culture
The human iPSC control lines (1210B2 and RPC771 (ReproCELL)) and the genome-edited derivative of RPC771 (ΔEx15) were maintained as previously described50,65. The cells were cultured under feeder-free conditions in…
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Arbuscular mycorrhizal fungi communities and glomalin mediate particulate and mineral-associated organic carbon formation in grassland patches
Bai, Y. & Cotrufo, M. F. Grassland soil carbon sequestration: current understanding, challenges, and solutions. Science 377, 603–608 (2022).
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