Horejsi, Z. et al. CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Mol. Cell 39, 839–850 (2010).
Boulon, S. et al. The Hsp90 chaperone controls…
Category: 5. Biology
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Lethal effects of ivermectin structures on malaria vectors and in silico analysis of interactions with their glutamate-gated chloride ion channels
Billingsley, P. et al. A Roadmap for the Development of Ivermectin as a Complementary Malaria Vector Control Tool. Am. J. Trop. Med. Hyg. 102, 3–24. https://doi.org/10.4269/ajtmh.19-0620 (2020).
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Inherited resilience | Nature Reviews Cancer
Clonal haematopoiesis of indeterminate potential (CHIP), the presence of somatic mutations linked to myeloid malignancies (MyMs) in the peripheral blood of healthy individuals, increases the lifetime risk of developing MyMs and other chronic…
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LINC01857 promotes clear cell renal cell carcinoma progression by scaffolding DNMT1 to suppress WIF1 expression
Young, M. et al. Renal cell carcinoma. Lancet 404, 476–491 (2024).
Siegel, R. L., Miller, K.D., Wagle, N.S. & Jemal, A. Cancer statistics, 2023. CA Cancer J. Clin. 73, 17–48 (2023).
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Integrative bioinformatics and molecular analysis revealed the roles of mTOR/S6K Axis, CASC15, and miR-30a-3p in laryngeal squamous cell carcinoma
Zhang, J., Wang, P. & Cui, Y. Long noncoding RNA NEAT1 inhibits the acetylation of PTEN through the miR-524-5p/HDAC1 axis to promote the proliferation and invasion of laryngeal cancer cells. Aging (Albany NY). 13 (22), 24850 (2021).
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Aberrantly expressed long noncoding RNAs in adipose-derived mesenchymal stem cells differentiation to nucleus pulposus-like cells
Hoffeld, K. et al. Patient-related risk factors and lifestyle factors for lumbar degenerative disc disease: a systematic review. Neurochirurgie 69, 101482. https://doi.org/10.1016/j.neuchi.2023.101482 (2023).
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The Parasite That Chemically Castrates Its Moth Host
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In addition to delivering painful stings, some species of wasps are parasites….
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Good and Bad Fats are Processed Differently
We need to consume fat to survive, but a new study has shown that the human body can process different types of fats in different ways. Over the years, studies have indicated that some types of fat are…
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Genetics Study Shows Anxiety Causes are Complex & Varied
It’s estimated that one in four adults will suffer from some type of anxiety disorder at some point, such as phobias of specific things; generalized anxiety that affects people over a long period of time; or…
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Fed on Reams of Cell Data, AI Maps New Neighborhoods in the Brain
The algorithm was also able to identify new neighborhoods, regions that previous neuroscience methods, including the Allen Mouse Brain Common Coordinate Framework, had missed. Take the striatum, a striped, vaguely C-shaped structure near the…
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