Determining the mechanisms of brain evolution by studying only a select number of organisms that have adapted to a restrictive survival environment is currently an inadequate approach. Here, we attempted a comparative analysis of the brain…
Category: 5. Biology
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C. elegans sperm and oocytes differentially transmit diet-induced adaptations to their progeny
Growth on novel bacteria reduces self-brood size
We assessed reproductive fitness by measuring hermaphrodite self-brood size as a primary metric to evaluate multigenerational adaptation. Specifically, we measured the total self-brood size of…
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Combination of genetic studies and animal modeling proposes TMPRSS9 as a candidate gene for serum K+ variations
Kario, K., Okura, A., Hoshide, S. & Mogi, M. The WHO global report 2023 on hypertension warning the emerging hypertension burden in Globe and its treatment strategy. Hypertens. Res. 47, 1099–1102 (2024).
Google…
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Vision-language model for report generation and outcome prediction in CT pulmonary angiogram
For diagnosis and report generation, we included a total of 69,761 paired CTPA image-report studies from 24,890 patients across three datasets: Brown University Health (BUH, n = 19,565), Johns Hopkins University (JHU, n = 1077), and the…
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Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus
COVID-19 induces systemic inflammation, oxidative stress, and hypoxia—pathophysiological processes increasingly linked to ocular diseases, including POAG38,39. Our findings align with emerging evidence that SARS-CoV-2 infection exacerbates…
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Integrated genomics with refined cell-of-origin subtyping distinguishes subtype-specific mechanisms of treatment resistance and relapse in diffuse large B-cell lymphoma
Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 2002;346:235–42.
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The functional of cathepsin L in the ontogenesis and reproductive regulation of the Asian corn borer, Ostrinia furnacalis
Burkness, E. C. et al. Efficacy and risk efficiency of sweet corn hybrids expressing a Bacillus thuringiensis toxin for Lepidopteran pest management in the Midwestern US. Crop Prot. 21, 157–169. https://doi.org/10.1016/S0261-2194(01)00080-1…
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Vertical transmission in field-caught mosquitoes identifies a mechanism for the establishment of Usutu virus in a temperate country
Paz, S. Climate change impacts on vector-borne diseases in europe: risks, predictions and actions. Lancet Reg. Health Eur. 1. (2021).
de Souza, W. M. & Weaver, S. C. Effects of climate change and human activities on vector-borne diseases. Nat….
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Replacing protruding domains of MrNV virus-like particles with sialic acid binding domains enhances binding to SARS-CoV-2 susceptible cells and reduces pseudovirus infection
The glycan profile of HEK293T and HEK293T-hACE2 cell line using lectin probes
To serve as a confirmation of the presence of sialylation in the ACE2-overexpressing HEK293T-hACE2 cells compared to the normal HEK-293 T cell line, whole cell protein…
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Neural network based AI model for lung health assessment
The methodology proposed in this study is illustrated in Fig. 1. The steps followed can be broadly divided into data acquisition, pre-processing, training and testing, and final decision. These steps are discussed in detail in the following…
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