McEwen, B. S. & Milner, T. A. Understanding the broad influence of sex hormones and sex differences in the brain. J. Neurosci. Res. 95, 24–39 (2017).
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Category: 5. Biology
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Global changes in synthesis rates and mRNA stabilities during adaptive responses to cell wall stress in yeast
Global kinetic analysis of mRNA levels, synthesis rates, and mRNA stabilities after cell wall stress
In recent years, our lab has characterized the global transcriptional response of S. cerevisiae to Congo Red, a dye that interferes with cell wall…
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Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis
Stationary and random burst events algorithm
Our approach to detecting burst events involves two main parts: automatic region selection and neural network classification. The first part is detecting the potential ROIs. The event detection…
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A Cross-Species Brain Magnetic Resonance Imaging and Histology Database of Vertebrates
Determining the mechanisms of brain evolution by studying only a select number of organisms that have adapted to a restrictive survival environment is currently an inadequate approach. Here, we attempted a comparative analysis of the brain…
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C. elegans sperm and oocytes differentially transmit diet-induced adaptations to their progeny
Growth on novel bacteria reduces self-brood size
We assessed reproductive fitness by measuring hermaphrodite self-brood size as a primary metric to evaluate multigenerational adaptation. Specifically, we measured the total self-brood size of…
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Combination of genetic studies and animal modeling proposes TMPRSS9 as a candidate gene for serum K+ variations
Kario, K., Okura, A., Hoshide, S. & Mogi, M. The WHO global report 2023 on hypertension warning the emerging hypertension burden in Globe and its treatment strategy. Hypertens. Res. 47, 1099–1102 (2024).
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Vision-language model for report generation and outcome prediction in CT pulmonary angiogram
For diagnosis and report generation, we included a total of 69,761 paired CTPA image-report studies from 24,890 patients across three datasets: Brown University Health (BUH, n = 19,565), Johns Hopkins University (JHU, n = 1077), and the…
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Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus
COVID-19 induces systemic inflammation, oxidative stress, and hypoxia—pathophysiological processes increasingly linked to ocular diseases, including POAG38,39. Our findings align with emerging evidence that SARS-CoV-2 infection exacerbates…
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Integrated genomics with refined cell-of-origin subtyping distinguishes subtype-specific mechanisms of treatment resistance and relapse in diffuse large B-cell lymphoma
Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 2002;346:235–42.
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The functional of cathepsin L in the ontogenesis and reproductive regulation of the Asian corn borer, Ostrinia furnacalis
Burkness, E. C. et al. Efficacy and risk efficiency of sweet corn hybrids expressing a Bacillus thuringiensis toxin for Lepidopteran pest management in the Midwestern US. Crop Prot. 21, 157–169. https://doi.org/10.1016/S0261-2194(01)00080-1…
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