Category: 5. Biology

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  • TdT/Cas12a-based biosensor for sensitive detection of DNA breakpoints in sperm cryopreservation

    TdT/Cas12a-based biosensor for sensitive detection of DNA breakpoints in sperm cryopreservation

    Detection principle

    In the described detection system, TdT is utilized to recognize the 3′-hydroxyl group (3′-OH) at sperm DNA break sites, which are formed during the freezing process due to adverse factors such as reactive oxygen species…

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  • Oxytranscriptome of soybean seedlings under short-term cadmium treatment

    Oxytranscriptome of soybean seedlings under short-term cadmium treatment

    Cultivation and treatment procedures

    Soybean (Glycine max L. cv. Nawiko) seeds were obtained from the Department of Genetics and Plant Breeding of the University of Life Sciences in Poznań, Poland. The seeds were surface sterilized (5 min in 75%…

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  • hMTR4 promotes p53 protein degradation and tumor growth by accelerating rRNA processing and regulating the RPL5-MDM2 axis

    hMTR4 promotes p53 protein degradation and tumor growth by accelerating rRNA processing and regulating the RPL5-MDM2 axis

  • Lingaraju M, Schuller JM, Falk S, Gerlach P, Bonneau F, Basquin J, et al. To process or to decay: a mechanistic view of the nuclear RNA exosome. Cold Spring Harb Symp Quant Biol. 2019;84:155–63.

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  • D-Amino acids affect Pseudomonas aeruginosa biofilm and quorum sensing molecules in lung infection models developed under a cystic fibrosis environment

    D-Amino acids affect Pseudomonas aeruginosa biofilm and quorum sensing molecules in lung infection models developed under a cystic fibrosis environment

  • Naddaf, M. 40 million deaths by 2050: toll of drug-resistant infections to rise by 70. Nature 633, 747–748 (2024).

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  • Reynolds, D. & Kollef, M. The epidemiology and…

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  • Early breast cancer detection via infrared thermography using a CNN enhanced with particle swarm optimization

    Early breast cancer detection via infrared thermography using a CNN enhanced with particle swarm optimization

    The dataset consists of breast thermal images from both healthy individuals and patients with diagnosed breast cancer. The dataset includes a variety of patient profiles to ensure diversity and robustness for research purposes. The patient…

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  • Gender differences in plasma element concentrations and associations between selenoprotein P and iron metabolism in a community-based cohort study

    Gender differences in plasma element concentrations and associations between selenoprotein P and iron metabolism in a community-based cohort study

    Validation of multi-elemental analysis

    To validate the multi-elemental analysis of plasma samples collected in the TMM Community-Based Cohort Study, we first determined the levels of 14 elements in pooled human plasma. Plasma samples were mixed…

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  • Effects of naphthalene, an aromatic hydrocarbon on the molecular and anatomical characteristics of the Portulaca oleracea plant

    Effects of naphthalene, an aromatic hydrocarbon on the molecular and anatomical characteristics of the Portulaca oleracea plant

    Plant cultivation

    The seeds of Purslane (P. oleracea) were sourced from the Azar Sabzin Company (Tabriz, Iran), and were cultivated in a seedling tray filled with peat moss within the greenhouse at Shiraz University, Shiraz, Iran during the 2023…

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  • Diagnosing pathologic myopia by identifying morphologic patterns using ultra widefield images with deep learning

    Diagnosing pathologic myopia by identifying morphologic patterns using ultra widefield images with deep learning

    Dataset construction

    We show details about the course of data acquisition and labeling. We perform essential data processing and stratified data partitioning to facilitate model training.

    The PSMM dataset consisted of five sub-sources: ShenzhenEye,…

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