Category: 5. Biology

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  • Correction: Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity

    Correction: Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity

    Correction: Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity

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  • A conserved coupling of transcriptional ON and OFF periods underlies bursting dynamics

    A conserved coupling of transcriptional ON and OFF periods underlies bursting dynamics

  • Lelli, K. M., Slattery, M. & Mann, R. S. Disentangling the many layers of eukaryotic transcriptional regulation. Annu. Rev. Genet. 46, 43–68 (2012).

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  • Identification of host cell surface proteins inhibiting furin dependent proteolytic processing of viral glycoproteins

    Identification of host cell surface proteins inhibiting furin dependent proteolytic processing of viral glycoproteins

    Biosafety

    All experiments with class 2 and 3 pathogens were performed in BSL2 or BSL3 laboratories of the University of Geneva. Experiments were approved by cantonal and federal authorities.

    Cell lines

    HEK293T (human embryonic kidney, ATCC) and…

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  • Human myelocyte and metamyelocyte-stage neutrophils suppress tumor immunity and promote cancer progression

    Human myelocyte and metamyelocyte-stage neutrophils suppress tumor immunity and promote cancer progression

  • Kolaczkowska, E. & Kubes, P. Neutrophil recruitment and function in health and inflammation. Nat. Rev. Immunol. 13, 159–175 (2013).

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  • Kang, H. et al….

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  • Bridging the gap: how sperm’s core structure explains male infertility

    Bridging the gap: how sperm’s core structure explains male infertility

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  • Distinct and shared intrinsic resting-state functional networks in children with idiopathic autism spectrum disorder and fragile X syndrome

    Distinct and shared intrinsic resting-state functional networks in children with idiopathic autism spectrum disorder and fragile X syndrome

  • Bhat S, Acharya UR, Adeli H, Bairy GM, Adeli A. Autism: cause factors, early diagnosis and therapies. Rev Neurosci. 2014;25:841–50.

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  • Volkmar FR, McPartland JC. From kanner to DSM-5:…

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  • Evaluating cognitive decline detection in aging populations with single-channel EEG features based on two studies and meta-analysis

    Evaluating cognitive decline detection in aging populations with single-channel EEG features based on two studies and meta-analysis

    Participants

    The first study recruited 80 patients from the inpatient rehabilitation department at Dorot Geriatric Medical Center, with a mean age of 73.51 (SD: 10.45) years, evenly distributed between males and females. Both groups exhibited a…

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  • A binding agreement | Nature Plants

    A binding agreement | Nature Plants

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  • Disruption of the cerebrospinal fluid–plasma protein balance in cognitive impairment and aging

    Disruption of the cerebrospinal fluid–plasma protein balance in cognitive impairment and aging

    To understand the relationships between CSF and plasma protein levels, we used the SomaScan platform to perform proteomics on paired CSF and plasma samples from 2,171 people, including 931 healthy controls and 1,240 participants with…

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