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Nobrega, F. L. et al. Targeting mechanisms of tailed…
Category: 5. Biology
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The next generation of colour pattern genomics
The next generation of colour pattern genomics
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A male-essential miRNA is key for avian sex chromosome dosage compensation
Ethics information
All animal procedures were conducted in compliance with national and international ethical guidelines and regulations. Mouse experiments were approved by the local animal welfare authorities at Heidelberg University Interfaculty…
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In vitro and in silico study and pharmacokinetic analysis of the acaricidal effectiveness of Cersium arvense extract against Rhipicephalus microplus
Cutler, S. J. et al. Tick-borne diseases and co-infection: current considerations. Ticks tick-borne Dis. 12 (1), 101607 (2021).
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Ullah, S. et al. First report of Anaplasma spp.,…
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When cellular reprogramming meets AI: towards de novo cell design
Decoding and reprogramming cells — the fundamental units of life — remains one of the most profound challenges in modern biology. Historically, the identity of a differentiated cell was viewed as fixed, much like a marble rolling down…
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Single-cell spatial analysis with Xenium reveals anti-tumour responses of CXCL13 + T and CXCL9+ cells after radiotherapy combined with anti-PD-L1 therapy
Study objectives and design
The aim of this study was to elucidate alterations in the immune environment after treatment with anti-PD-L1-CRT and to investigate the underlying mechanisms at the single-cell level via use of Xenium. First, we…
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Design, synthesis and evaluation of benzodioxole and bromofuran tethered 1,2,4-triazole hybrids as potential anti breast cancer agents with computational insights
Chemistry
In the present study, six 1,2,4-triazole hybrids were synthesized, as illustrated in Schemes 1 and 2. The process begins with the esterification of 3,4-(methylenedioxy)phenylacetic acid and 5-bromofuranoic acid, forming the…
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The impact of vaccine booster doses on specific B- and T-lymphocyte dynamics in Thai healthcare personnel following COVID-19 vaccination
SARS-CoV-2 continues to circulate globally, and COVID-19 vaccine innovations are in development (e.g., vaccines that provide broad protection and long-lasting immunity, improvements in vaccine stability)19,20, requiring new knowledge to broaden…
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Trans-organ analysis of gene co-expression networks reveals a mobile long-distance regulator that balances shoot and root development in Arabidopsis
Molnar, A. et al. Small silencing RNAs in plants are mobile and direct epigenetic modification in recipient cells. Science 328, 872–875 (2010).
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Thieme, C. et al….
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Evolving a bat wing by reusing an existing gene program
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This is a summary of: Schindler, M. et al. Comparative single-cell analyses reveal evolutionary repurposing…
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