Structure of the human MVP-PARP4 complex
Full-length constructs of human MVP and PARP4 were cloned into baculoviral vectors for overexpression in insect cells, which do not produce endogenous MVP. An initial attempt to purify the MVP-PARP4 complex…
Category: 5. Biology
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Pseudomonas aeruginosa carriage and associated risk factors in healthy individuals and patients from Rotterdam, Rome, and Jakarta
Healthy individuals
In Rotterdam, 2292 healthy individuals were invited to participate via an information letter. The outreach was subsequently broadened through social media, local newspapers, and by being featured on a local radio station…
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EIF3B stabilizes MAP2K2 to activate the ERK pathway and promote the progression of laryngeal squamous cell carcinoma
The high expression of EIF3B in LSCC is correlated with survival
From Gene Expression Omnibus (GEO) database, we identified that EIF3B was upregulated in LSCC tissue samples (n = 9) compared with paired non-tumor tissue samples (n = 9)…
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Addendum: Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale
In the fuels market, the Renewable Energy Directive (EU)7, Renewable Transport Fuels Organization (UK)8 and Carbon Offsetting Reduction Scheme for International Aviation (global)9 all treat CCU products made from industrial waste off-gases the…
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Effects of microclimate variation on insect persistence under global change
International Union for Conservation of Nature (IUCN). The IUCN Red List of Threatened Species. IUCN https://www.iucnredlist.org (2025).
Wilson, R. J. & Fox, R. Insect responses to global change offer signposts for biodiversity and conservation….
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Bioprospecting endophytic fungi of forest plants for bioactive metabolites with anticancer potentials
Screening fungal extracts for their cytotoxic potentials
The cytotoxic activities of the crude fungal extracts (cell-free filtrate and biomass) were evaluated against three different cancer cell lines human melanoma (A375), breast adenocarcinoma…
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Viromics approaches for the study of viral diversity and ecology in microbiomes
Koonin, E. V., Kuhn, J. H., Dolja, V. V. & Krupovic, M. Megataxonomy and global ecology of the virosphere. ISME J. 18, wrad042 (2024).
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Koonin, E. V. et al….
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Age-dependent neuroinflammation response to voluntary wheel running and Metformin treatment in the frontal cortex of ovariectomized female mice
Beam, C. R. et al. Differences between women and men in incidence rates of dementia and alzheimer’s disease. J. Alzheimers Dis. 64, 1077–1083 (2018).
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Diversity and transmission and zoonotic potential of microbes in true insectivores
Jones, K. E. et al. Global trends in emerging infectious diseases. Nature 451, 990–993 (2008).
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Wolfe, N. D., Dunavan, C. P. & Diamond, J….
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In vivo measurement of an Apelin gradient with a genetically encoded APLNR conformation biosensor
Ethical statement
Zebrafish husbandry and maintenance was performed under standard conditions in accordance to institutional (Philipps-University Marburg) as well as national ethical and animal welfare guidelines approved by the ethics commission…
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