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Category: 5. Biology

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  • Bioinformatic exploration reveals features of tenpIN family of type III toxin-antitoxin systems in bacteria and viruses

    Bioinformatic exploration reveals features of tenpIN family of type III toxin-antitoxin systems in bacteria and viruses

    TenpIN TA systems are widespread in the microbial world

    The initial bioinformatics study conducted over a decade ago identified 25 putative11 tenpIN sequences, of which 11 were well-annotated and remain in current…

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  • Breast carcinomas associated with microglandular adenosis are linked to germline alterations in homologous recombination-deficiency genes

    Breast carcinomas associated with microglandular adenosis are linked to germline alterations in homologous recombination-deficiency genes

    Study cohort

    Our cohort included thirty-eight patients diagnosed with either IBC-MGA (n = 34) or BCis-MGA (n = 4) who had previously undergone germline genetic testing (Table 1 and Supplementary Table S1). The median age at diagnosis…

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  • Shiga toxin-producing Escherichia coli plasmid diversity reveals virulence potential and control opportunities in animal hosts

    Shiga toxin-producing Escherichia coli plasmid diversity reveals virulence potential and control opportunities in animal hosts

  • Kaper, J. B., Nataro, J. P. & Mobley, H. L. T. Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2, 123–140 (2004).

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  • Maldonado, N. et al. Whole-genome characterisation of Escherichia…

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  • Metabolic reprogramming with ultrasound-responsive nanovesicles

    Metabolic reprogramming with ultrasound-responsive nanovesicles

    Metabolic reprogramming with ultrasound-responsive nanovesicles

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  • Dominant eye-dependent lateralized behavior in the scale-eating cichlid fish, Perissodus microlepis

    Dominant eye-dependent lateralized behavior in the scale-eating cichlid fish, Perissodus microlepis

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  • Reiss, M. & Reiss, G. Ocular dominance: some family data. Laterality 2 (1), 7–16 (1997).

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  • LARS2 DNA methylation predicts the prognosis in colon cancer

    LARS2 DNA methylation predicts the prognosis in colon cancer

    The basis of DNA methylation modifiers

    The present study collected 20 DNA methylation genes10, including 3 writers (TET1, TET2, TET3), 3 erasers (DNMT1, DNMT3A, DNMT3B) and 14 reads (MBD1, MBD2, MBD3, MBD4, ZBTB33, ZBTB38, ZBTB4, UHRF1, UHRF2,…

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  • Perillyl alcohol promotes autophagy by suppressing the PI3K-AKT-mTOR signalling pathway in osteoarthritic chondrocytes in vitro

    Perillyl alcohol promotes autophagy by suppressing the PI3K-AKT-mTOR signalling pathway in osteoarthritic chondrocytes in vitro

  • Wang, Y., Li, J., Zhou, J., Qiu, Y. & Song, J. Low-intensity pulsed ultrasound enhances bone marrow-derived stem cells-based periodontal regenerative therapies. Ultrasonics 121, 106678 (2022).

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  • Validation of a bitmap of genes involved in cherry fruit cracking by digital PCR and qPCR, suitable for plant breeding

    Validation of a bitmap of genes involved in cherry fruit cracking by digital PCR and qPCR, suitable for plant breeding

    Plant material

    Experiments were carried out in commercial orchards located in Resende region, Portugal (41°06’52.8″N 7°56’13.3″W, altitude 246 m – Cv. Burlat, and 41°04’55.3″N 7°53’35.2″W, altitude 615 m – Cv. Sweetheart). The…

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  • Retraction Note: Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy

    Retraction Note: Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy

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