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Category: 5. Biology
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Intestinal pathogens override hunger-driven decision-making via immune regulation of central serotonin signaling in C. elegans
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Hu, H. Reward and…
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Minimum reporting elements for ophthalmic vision–language model studies
I read with great interest the study by Meng and colleagues evaluating three vision–large language models (VLMs)—GPT-4o, GPT-4V, and Gemini 1.5 Pro—on ultra-widefield (UWF) fundus photographs for the description and classification of…
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Brains of ‘super agers’ are still strong producers of new neurons
Adults whose brains still have strong neuron production seem to have better memory and cognitive function than do those in whom the ability wanes, finds a study published today in Nature1. The authors examined brain samples from deceased donors…
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Targeting de novo pyrimidine synthesis confers vulnerability to copper-mediated ATR inactivation in PARP inhibitor-resistant ovarian cancer
Lord, C. J. & Ashworth, A. PARP inhibitors: synthetic lethality in the clinic. Science 355, 1152–1158 (2017).
Scott, C. L., Swisher, E. M. & Kaufmann, S. H. Poly (ADP-ribose) polymerase…
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Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in pneumonia-associated sepsis
Shankar-Hari, M. et al. Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies. Lancet Respir. Med. 12, 323–336 (2024).
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Target-stabilized base editors enable robust high-fidelity RNA editing
Crick, F. Central dogma of molecular biology. Nature 227, 561–563 (1970).
Manning, K. S. & Cooper, T. A. The roles of RNA processing in translating genotype to phenotype. Nat. Rev. Mol. Cell…
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Correction: METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation
Correction: METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation
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The molecular evolution of vertebrate organs
Striedter, G. F. & Northcutt, R. G. Brains Through Time (Oxford Univ. Press, 2019).
Olson, E. N. Gene regulatory networks in the evolution and development of the heart. Science 313, 1922–1927 (2006).
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An insight into comparative sex based proteomic profiling of Hilsa Tenualosa ilisha towards domestication and aquaculture
Ueda, H. Physiological mechanisms of imprinting and homing migration in Pacific salmon Oncorhynchus spp. J. Fish Biol. 81, 543–558 (2012).
Nath, A. K., Banerjee, B. & Ray, S. Socio-economic…
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