Category: 5. Biology

A new study reveals that vesicles packed with healthy mitochondria can supercharge tissue repair and combat chronic disease, paving the way for next-generation regenerative treatments.

Study: Harnessing tissue-derived…

Plant and insect materials

Solanum nigrum L. seeds underwent sterilization and vernalization at 4 °C for 24 h before germination on Murashige and Skoog (MS) medium. Seedlings were subsequently transplanted into sterile culture bottles or…

Architecture of MtCNGC15b

To explicate the structure of MtCNGC15, the expression level and cryo-EM performance of three isoforms MtCNGC15a/b/c were individually examined using insect cells and mammalian cells. In spite of high sequence…

Mice

Ripk^1tm1.1Pvdb, B6.129(Cg)-Foxp3^{tm4(YFP/icre)Ayr}/J, Foxp3^{tm1(CD2/CD52)Shori}, and B6.129-Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/J mice have been previously described [56,57,58,59]. Ripk1^ΔFoxp3 mice and Ripk1^fl/fl Foxp3^Cre/wt mice were generated by…

This research complies with all relevant ethical regulations. Appropriate study approvals are included in the relevant sections below.

Zebrafish

Cloning

For the tfap2b-GFP reporter, two open areas of chromatin that were statistically enriched in…

Tibial loading metrics

Tibial bending moments

The experimental test was carried out for 54 immature oocytes. At first, each oocyte was individually injected into the channel with a very low flow rate of about 0.05 µl per minute. The flow was then increased stepwise at intervals of 10 s….

The segAB locus and genomic neighbour conservation

The segAB genes are found widely on chromosomes of Thermoproteota and Euryarchaeota. The 3’ end of segA overlaps with the 5’ end of segB in most genera, suggesting that the genes form a single…