Animals
The Trpv4 WT, Trpv4 KO, Trpv4 WT Cx3cr1eGFP/+, and Trpv4 KO Cx3cr1eGFP/+ mice used in this study were obtained by in-house breeding. Trpv4 KO mice were obtained thanks to the Laboratory of Ion Channel Research at KU Leuven (generated as…
Category: 5. Biology
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Metabolomic and chemometric profiling of crimson grapes during drying and its impact on antidiabetic activity
Tentative annotation of grape metabolites
A total of 50 metabolites were tentatively annotated from the different analyzed samples, including fresh and dehydrated grape extracts, using UPLC–QTOF-MS/MS analysis. Following the metabolomics…
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Author Correction: MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Mitochondrial proteins go public and novel interactions: insights from surfaceome mapping
The cell surface is the main interface for external communication and immune modulation, yet our understanding of how cell surface proteins are spatially organized and interact remains incomplete. New techniques have evaluated specific…
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Author Correction: Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Emergence of pathogenic recombinant coronavirus in cats
Coronaviruses (CoVs), which are present in humans, companion animals, livestock and wildlife, can frequently recombine, potentially leading to cross-species transmission. Feline CoV (FCoV) has two biotypes: feline enteric coronavirus (FECV,…
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Targeting SLC7A5 in lung squamous cell carcinoma: implications for cancer metabolism shift and boron neutron capture therapy resistance
Chemicals and reagents
RPMI-1640 (Gibco™, 31800-014, USA) and fetal bovine serum (FBS, Gibco™, 10437-028, USA) were procured from GIBCO-BRL. Chloroquine was obtained from Cell Signaling Technology Inc. (CST, 14774, USA), while rapamycin was…
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Macrophage-T cell interactions promote SLAMF1 expression for enhanced TB defense
Ethics consideration
NYU School of Medicine and Washington University School of Medicine Institutional Animal Care and Use Committees approved all mouse work (Protocol# 21-0245 and 24-0201). Euthanasia was performed in accordance with the 2013…
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Resolving the structural basis of therapeutic antibody function in cancer immunotherapy with RESI
Materials
Right-handed DNA oligonucleotides, modified with C3-azide or 5’-Cy3B, were ordered from Metabion. Left-handed DNA sequences were purchased from Biomers. Ultrapure water (cat: 10977-035), Tris 1 M pH 8 (cat: AM9855G), EDTA…
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