Ethics statements
All experiments were performed according to the ethical standards of the institute. Animal procedures including biopsy collection were approved by the Institute Animal Ethics Committee, ICAR-National Dairy Research Institute…
Category: 5. Biology
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Live vaccine development through targeted protein degradation
Vaccination is one of the most effective ways to protect populations from viral infections. A popular method for vaccine development involves attenuating viruses to weaken their ability to cause disease for use as live vaccines. Live attenuated…
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Diagnostic yield of trio exome sequencing as a first-tier test for identifying genetic causes of pregnancy loss
Heaney S, Tomlinson M, Aventin A. Termination of pregnancy for fetal anomaly: a systematic review of the healthcare experiences and needs of parents. BMC Pregnancy Childbirth. 2022;22:441.
Google…
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Single-cell RNA sequencing analysis revealed the immunosuppressive remodeling of tumor-associated macrophages mediated by the MIF-CD74 axis in gastric cancer
Single-cell atlas of non-malignant and malignant gastric tissues
To fully characterize the single-cell profile of gastric malignancies, a total of 14 samples were collected, including 11 patients with primary tumor (GC) gastric cancer and 3…
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Metabolic reprogramming and prognostic insights in molecular landscapes driven by glycolysis in ovarian cancer
Characterizing GRGs in OC progression dynamics
A total of 457 GRGs were identified as significantly differentially expressed when comparing the transcriptomes of ovarian cancer samples from the TCGA-OC dataset with those of normal ovarian tissues…
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New method genetically blocks mosquitoes from transmitting malaria
Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.
Recent efforts to…
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Dinosaurs roamed in multi-species herds, fossilized footprints show
In Africa, wildebeest and zebra roam the plains in multi-species herds. The…
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Climate change may be pushing fungal allergy season earlier
There’s no rest for allergy sufferers.
Fungal allergy season gets going an average of 22 days earlier than it did 20 years ago, researchers report in the July GeoHealth. Rising temperatures and altered precipitation are linked to…
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Skin wrinkles because it stretches like Silly Putty
Everybody’s skin wrinkles with age, but the actual science behind why it…
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New collaborative effort harnesses AI to drive ALS drug discovery in Louisiana
Answer ALS is proud to announce the launch of a groundbreaking collaborative initiative aimed at accelerating AI-powered drug discovery for ALS and other neurodegenerative diseases. This effort, known as the Louisiana AI Drug…
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