Nordestgaard BG, Chapman MJ, Humphries SE, Ginsberg HN, Masana L, Descamps OS, et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease:…
Category: 5. Biology
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MRIcroGL: voxel-based visualization for neuroimaging
MRIcroGL: voxel-based visualization for neuroimaging
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Fungal keratitis: slow, relentless, and breaching
Fungal keratitis: slow, relentless, and breaching
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Rational adjuvant selection for the neonatal period shapes unique and lasting immune polarization in mice
Reed, S. G., Orr, M. T. & Fox, C. B. Key roles of adjuvants in modern vaccines. Nat. Med. 19, 1597–1608 (2013).
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Pulendran, B., P, S. A. & O’Hagan, D. T. Emerging…
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A mutual co-recognition mechanism ensures the proper assembly of heterotrimeric kinesin-2 for intraflagellar transport
Biochemical assembly of the KLP-20/KLP-11/KAP-1 complex without motor domains
To investigate the mechanism underlying the assembly of heterotrimeric kinesin-2, we initiated this study with the biochemical assembly and characterization of the…
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Use of a BMI-independent biomarker-based prostate cancer risk score to identify and triage individuals at risk of prostate disease
tPSA levels in the total sample and biomarker cohorts
The patient demographics for the total sample cohort (n = 25,356) included in this study are described in Table 1. To assess PCa risk, 95.5% (24,214/25,356) of the total sample cohort had…
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Pharmacological Evaluation of active compounds in papaya associated with thrombocytopenia inhibition in dengue patients through in silico approaches
Quantum analysis
Geometry optimization
The geometries of five ligands – olean-12-ene, quercetin, apigenin, luteolin and kaempferol — were optimized and characterized. First, each ligand was optimized using a Dreiding-based forcefield, followed by…
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Modeling proximalisation in axolotl limb regeneration
Animal husbandry
Care of axolotls and all experimental protocols used in this study were approved by the United Kingdom Home Office and the State of Saxony, Germany. All methods were performed in compliance with the Animals -Scientific…
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Prognostic implications of complement C1q-like 4 expression in breast cancer
BC is one of the most common malignancies worldwide and the leading cause of cancer-related mortality among women. In recent years, the incidence of BC has been increasing significantly due to changes in lifestyle, dietary habits, and…
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Birth of India’s first cloned cattle and analysis of its health and reproduction status: A case study
Ethics statements
All experiments were performed according to the ethical standards of the institute. Animal procedures including biopsy collection were approved by the Institute Animal Ethics Committee, ICAR-National Dairy Research Institute…
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