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Category: 5. Biology
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Towards a prognostic biomarker for multiple sclerosis
Multiple sclerosis is an autoinflammatory and neurodegenerative disease of the central nervous system that involves demyelination and axonal damage. Evidence strongly suggests that Epstein–Barr virus (EBV) is involved in disease pathology. It…
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Comparative transcriptome analysis reveals the potential mechanism of seed germination promoted by trametenolic acid in Gastrodia elata Blume
TA extraction and separation
It was isolated and purified from the alcoholic extract of Trametes lactinea (Berk.) Pat by our laboratory (Hubei Key Laboratory of Natural Products Research and Development, Three Gorges University). Specific methods:…
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A Bayesian nonparametric method for jointly clustering multiple spatial transcriptomic datasets and simultaneous gene selection
Let \({\textbf{Y}}_{j}\in {\mathbb {R}}^{n_j\times p}\) denote gene expression for \(n_j\) cells and p genes in group/donor \(j=1,\dots , J\) and let \({\textbf{X}}_j\in {\mathbb {R}}^{n_j\times 2}\) denote the matching spatial coordinates of the…
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Surfice: visualizing neuroimaging meshes, tractography streamlines and connectomes
Marcus, D. S. et al. Front. Neuroinform. 5, 4 (2011).
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Tournier, J.-D. et al. Neuroimage 202, 116137 (2019).
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Spatial transcriptomics reveals macrophage domestication by epithelial cells promotes immunotherapy resistance in small cell lung cancer
Spatial single-cell atlas of SCLC patients with distinct treatment efficacies
Eighteen extensive SCLC patients who received a combination of immunothearpy with chemotherapy were enrolled. Among them, 8 patients had progressive disease (PD), and 10…
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Genome wide association studies in yam reveal the challenge of high heterozygosity
Genetic material and plant phenotyping
A comprehensive study was conducted using 173 genotypes of D. rotundata, comprising 86 elite breeding clones, 77 genebank accessions, and ten farmers’ varieties. The detailed information regarding these…
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Inhibition of anti-apoptotic Bcl-2 family members promotes synergistic cell death with ER stress inducers by disrupting autophagy in glioblastoma
Price M, Ballard C, Benedetti J, Neff C, Cioffi G, Waite KA, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2017-2021. Neuro Oncol. 2024;26:vi1–vi85.
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Physical and psychological optimization of tele-exercise programs by establishing guidelines
Glossary section—operative definitions
Experts agreed on the operative definitions from the literature and enriched them with further details. The experts agreed on the following statements: Tele-exercise, which originally started as a branch of…
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