Category: 5. Biology

Biochemical assembly of the KLP-20/KLP-11/KAP-1 complex without motor domains

To investigate the mechanism underlying the assembly of heterotrimeric kinesin-2, we initiated this study with the biochemical assembly and characterization of the…

tPSA levels in the total sample and biomarker cohorts

The patient demographics for the total sample cohort (n = 25,356) included in this study are described in Table 1. To assess PCa risk, 95.5% (24,214/25,356) of the total sample cohort had…

Quantum analysis

Geometry optimization

The geometries of five ligands – olean-12-ene, quercetin, apigenin, luteolin and kaempferol — were optimized and characterized. First, each ligand was optimized using a Dreiding-based forcefield, followed by…

Animal husbandry

Care of axolotls and all experimental protocols used in this study were approved by the United Kingdom Home Office and the State of Saxony, Germany. All methods were performed in compliance with the Animals -Scientific…

BC is one of the most common malignancies worldwide and the leading cause of cancer-related mortality among women. In recent years, the incidence of BC has been increasing significantly due to changes in lifestyle, dietary habits, and…

Ethics statements

All experiments were performed according to the ethical standards of the institute. Animal procedures including biopsy collection were approved by the Institute Animal Ethics Committee, ICAR-National Dairy Research Institute…