Around two-thirds of adolescents with cannabis use disorder (CUD) fail to complete rehabilitation in the US. The corresponding study was published in Pediatric Reports. The findings may be used to aid the…
Category: 5. Biology
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Emma’s Gene – Life Sciences | Weizmann Wonder Wander
Emma Broadbent was born nine years ago in Dallas, Texas, with distinctive facial features. From birth, she suffered from muscle weakness and breathing problems, spending her first weeks in a neonatal intensive care unit. Her doctors, unable to…
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A tiny dinosaur bone just rewrote the origin of bird flight
The evolutionary path from dinosaurs to birds included the development of a tiny wrist bone that ultimately proved crucial for stabilizing wings in flight. A new study suggests that the bone appeared in bird ancestors millions of years earlier…
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Reactivating silent genes offers hope for Rett syndrome treatment
Researchers led by UC Davis Health scientist Sanchita Bhatnagar have developed a promising gene therapy that could treat Rett syndrome. The therapy works on reactivating healthy but silent genes responsible for this rare disorder…
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Novel start codon variant in the 5’UTR of LDLR associated with familial hypercholesterolaemia
Nordestgaard BG, Chapman MJ, Humphries SE, Ginsberg HN, Masana L, Descamps OS, et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease:…
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MRIcroGL: voxel-based visualization for neuroimaging
MRIcroGL: voxel-based visualization for neuroimaging
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Fungal keratitis: slow, relentless, and breaching
Fungal keratitis: slow, relentless, and breaching
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Rational adjuvant selection for the neonatal period shapes unique and lasting immune polarization in mice
Reed, S. G., Orr, M. T. & Fox, C. B. Key roles of adjuvants in modern vaccines. Nat. Med. 19, 1597–1608 (2013).
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Pulendran, B., P, S. A. & O’Hagan, D. T. Emerging…
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A mutual co-recognition mechanism ensures the proper assembly of heterotrimeric kinesin-2 for intraflagellar transport
Biochemical assembly of the KLP-20/KLP-11/KAP-1 complex without motor domains
To investigate the mechanism underlying the assembly of heterotrimeric kinesin-2, we initiated this study with the biochemical assembly and characterization of the…
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Use of a BMI-independent biomarker-based prostate cancer risk score to identify and triage individuals at risk of prostate disease
tPSA levels in the total sample and biomarker cohorts
The patient demographics for the total sample cohort (n = 25,356) included in this study are described in Table 1. To assess PCa risk, 95.5% (24,214/25,356) of the total sample cohort had…
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