In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at microscopic resolution, enabling researchers to measure all expressed mRNA…
Category: 5. Biology
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New structural insights pave way for hantavirus vaccines
Hantaviruses, transmitted from rodents to people, have a death rate approaching 40%. They’re found around the world, and because there are no approved vaccines or treatments, they’re among the pathogens of highest concern for future…
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Protein partnership enhances innate immune sensing of viral RNA
Study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science Tokyo. Using cryo-electron microscopy and high-speed atomic force microscopy, they found that LGP2 binds to…
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Mendelian randomization study reveals opposing roles for IL6 and IL6R in long-term mortality
A new research paper was published in Volume 18 of Aging-US on February 6, 2026, titled “Causal effects of inflammation on long-term mortality: a Mendelian randomization study.”
Led by Eliano P. Navarese from Department of Life…
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How immune cells spot viral RNA fast: LGP2 helps MDA5 respond to short dsRNA
A study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science Tokyo. Using cryo-electron microscopy and high-speed atomic force microscopy, they found that LGP2 binds to viral RNA and…
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Identification of GLDN+ odontogenic stem cells as crucial for human tooth development and regeneration
scRNA-seq reveals the heterogeneity of human DP cells
To distinguish the heterogenous cells populations in the DP, we analyzed scRNA-seq data from the early root development stage (when the root length is less than one-third of its final length)…
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Bone marrow stromal cells enhance chondrocyte function and autophagy via mTOR signaling
Zhou, X. et al. Hyoid bone position in patients with and without temporomandibular joint osteoarthrosis: A Cone-Beam computed tomography and cephalometric analysis. Pain Res. Manag. 2021, 4852683 (2021).
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Subcellular localization and differential expression provide insights into the putative function of the nematode resistance gene Hs4
Romeiras, M. M. et al. Evolutionary and biogeographic insights on the Macaronesian Beta-Patellifolia species (Amaranthaceae) from a time-scaled molecular phylogeny. PLoS One 11, e0152456. https://doi.org/10.1371/journal.pone.0152456 (2016).
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Botulinum toxin-induced masseter muscle atrophy is associated with impaired autophagic flux without signs of apoptosis in mice
Liu F, Steinkeler A. Epidemiology, diagnosis, and treatment of temporomandibular disorders. Dent Clin North Am. 2013;57:465–79.
Almukhtar RM, Fabi SG. The Masseter muscle and its role in facial…
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Early and diverse lipid consumption by Saccharomyces cerevisiae: an extensive targeted lipidomics approach and new perspectives for managing wine fermentation
Klug, L. & Daum, G. Yeast lipid metabolism at a glance. FEMS Yeast Res. 14, 369–388 (2014).
Mbuyane, L. L., Bauer, F. F. & Divol, B. The metabolism of lipids in yeasts and applications in…
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