High cell content of reactive oxygen species (ROS) could result in oxidative stress, and antioxidants prevent their formation and inhibit their activity2. Certain antioxidants could have beneficial effects on colorectal cancer initiation and…
Category: 5. Biology
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Pericyte-mediated regulation of angiogenesis during cutaneous wound healing in adult zebrafish
Conditional ablation of mural cells in zebrafish larvae
To clarify the roles of pericytes in regulating angiogenesis during wound healing, we generated a transgenic zebrafish line that enables the conditional ablation of mural cells by employing…
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The role of glucocorticoids in hepatocellular carcinoma through integrated bioinformatics analysis and experimental validation
Tumor and control group differential expression analysis and GSEA enrichment analysis
Through comparing tumor and control groups, 751 DEGs were identified, showing a statistically significant difference between the two groups (|(log2FC)| >1.5, P…
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A systematic benchmark of integrative strategies for microbiome-metabolome data
In this section, we describe the data simulation process, the methods tested for the four key analytical questions, and the evaluation metrics used to assess their performance.
Simulation setups
Microbiome and metabolome data were simulated using…
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Neonatal acute kidney injury and neurodevelopmental impairment: investigating associations in very low birthweight infants
Study population
We conducted a single-center, retrospective cohort study of VLBW infants admitted to the Medical University of South Carolina (MUSC) Neonatal Intensive Care Unit (NICU) between January 1, 2018, to December 31, 2021, and evaluated…
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Neighbourhood diversity increases tree growth in experimental forests more in wetter climates but not in wetter years
Griscom, B. W. et al. Natural climate solutions. Proc. Natl Acad. Sci. USA 114, 11645–11650 (2017).
Google Scholar
Loreau, M. et al. Biodiversity as insurance:…
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Scientists open new atlas of genetic diversity with advanced sequencing
A landmark study harnesses long-read sequencing to reveal vast, previously undetected structural variations in human DNA, reshaping our understanding of genetics and disease potential.
Study: Structural variation in 1,019…
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Warming Climate Sparks Innovative Wildlife Protection Measures in Guatemala
Scientists with the Wildlife Conservation Society have documented a remarkable diversity of wildlife visiting the artificial watering holes in Guatemala’s Maya Forest.
Jaguars get relief from the heat at an artificial waterhole in Guatemala….
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Analytical Ultracentrifugation (AUC) for Characterization of Lipid Nanoparticles (LNPs): A Comprehensive Review
Lipid nanoparticles (LNPs) and liposomes (Figure 1) have revolutionized the medical field by serving as carriers for a wide range of therapeutic molecules,
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