Category: 5. Biology

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  • How the American Cancer Society is tackling the collaboration challenge in cancer research

    How the American Cancer Society is tackling the collaboration challenge in cancer research

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    Collaboration is key to advancing cancer research, but institutional silos, fragmented data, and complex workflows often slow progress. Researchers need secure, scalable environments that enable seamless data sharing…

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  • Glutamatergic synaptic resilience to overexpressed human alpha-synuclein

    Glutamatergic synaptic resilience to overexpressed human alpha-synuclein

    Primary hippocampal neuronal cultures from rats

    Preparation of primary hippocampal neuronal cultures from E18 Wistar rat embryos was carried out as previously described with slight modifications65,66. All animal procedures were performed in…

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  • A citrullinated histone H3 monoclonal antibody for immune modulation in sepsis

    A citrullinated histone H3 monoclonal antibody for immune modulation in sepsis

    A thematic approach to achieve optimization of the humanized CitH3 monoclonal antibody

    To create the humanized hCitH3-mAb from the original mouse antibody40, a multi-step approach was used to maintain binding specificity while reducing…

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  • Recreating fibroblast diversity in vitro by activating transcription factors

    Recreating fibroblast diversity in vitro by activating transcription factors

    Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

    This is a summary of: Southard, K. M. et al. Comprehensive transcription factor perturbations recapitulate…

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  • Author Correction: Small circular RNAs as vaccines for cancer immunotherapy

    Author Correction: Small circular RNAs as vaccines for cancer immunotherapy

  • These authors contributed equally: Yu Zhang, Xiang Liu.

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  • Deeper human proteome profiling with higher throughput via optimized ion processing

    Deeper human proteome profiling with higher throughput via optimized ion processing

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    Proteomics has advanced to allow for the acquisition of comprehensive human proteomes with high throughput and accurate and precise quantitation using narrow-window data-independent acquisition (DIA) mass…

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