Study design
An in silico approach depicted in Figure S2 and utilizes bioinformatics computational methods, specifically reverse vaccinology and molecular docking techniques, was used in this study. Figure 1 represents the methodology’s…
An in silico approach depicted in Figure S2 and utilizes bioinformatics computational methods, specifically reverse vaccinology and molecular docking techniques, was used in this study. Figure 1 represents the methodology’s…
A total of 5110 patients were enrolled to the study, among whom 117 presented with BrM either at initial presentation or during their follow-up. The baseline characteristics of the entire cohort are presented in Table 1. Median age at diagnosis…
Two original germ-free strains BALB/cAnSlac (BC) and Kunming (KM) were bred in Shanghai Tenth People’s Hospital, Tenth People’s Hospital of TongJi University in Shanghai, China. The SPF NOD/SCID Il2rg–/– (NSG) strain was purchased…
Consistent with the prior observation in Sandkhol Carp, we found that zebrafish NPCs, which are fluorescently labelled in the Tg(lhx1a:EGFP) transgenic line7,16,…
This phase 2 single-arm, open-label trial (ClinicalTrials.gov NCT05348213) adopted a prospective cohort design. Enrollment was restricted to R/R DLBCL patients. Participant inclusion criteria included: age 18–75…
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In this study, the enhanced immunogenic response and protective efficacy of the BtaE antigen against B. melitensishas been demonstrated in a murine model through its incorporation into the Lpp-OmpA-BtaE construct. The integration of computational…
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