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This is a summary of: Yu, J. X. et al. The GENEVA platform models tumor mosaicism to reveal variations of…
Category: 5. Biology
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Heterogeneity and immune microenvironment of early invasive estrogen receptor-positive breast cancer reveal an immune-rich subset
DeSantis, C. E. et al. Breast cancer statistics, 2019. CA Cancer J. Clin. 69, 438–451 (2019).
Allison, K. H. et al. Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP…
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Dynamin optimizes protein-membrane interactions for fission
We study lipid bilayers and membrane tubes, and the effect of proteins on their fission behavior using self-consistent field theory (SCFT), building on our previous work9,10,51. In order to study the rearrangement of lipid bilayers during…
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Novel universal domain-centric method for protein classification
Cohen, P. The origins of protein phosphorylation. Nat. Cell. Biol. 4, E127–130 (2002).
Johnson, L. N., Lowe, E. D., Noble, M. E. M. & Owen, D. J. The structural basis for substrate…
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Lysine β-hydroxybutyrylation as a drought-responsive epigenetic mark in rice
Protein post-translational modifications (PTMs), such as acetylation and methylation, are established as crucial epigenetic marks in eukaryotic cells. Recent advances in mass spectrometry (MS) have…
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Multimodal multi-instance learning for cardiopulmonary exercise testing performance prediction
Bozkurt, B. et al. HF STATS 2024: Heart failure epidemiology and outcomes statistics an updated 2024 report from the heart failure society of America. J. Card. Fail 31, 66–116 (2025).
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High-frequency biparental inheritance of plant mitochondria upon chilling stress and loss of a genome-degrading nuclease
An experimental system to detect paternal mitochondrial transmission
The robust detection of paternal leakage in mitochondrial inheritance requires a high-throughput screening strategy. To identify a screenable phenotypic marker, we evaluated…
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An interfacial-intramolecular electron highway for accelerated electrocatalytic CO2 reduction by an O2-tolerant formate dehydrogenase
Liu, Z., Wang, K., Chen, Y., Tan, T. & Nielsen, J. Third-generation biorefineries as the means to produce fuels and chemicals from CO2. Nat. Catal. 3, 274–288 (2020).
Gleizer, S. et al….
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Multicenter ex vivo evaluation of an α-mannosidase–targeted fluorescent probe for intraoperative margin assessment in breast cancer
Taguchi, M. et al. Detection capability of the Medical Imaging Projection System for sentinel lymph node biopsy in patients with breast cancer with and without neoadjuvant chemotherapy: a retrospective study. Breast Cancer. 32, 834–840 (2025)….
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Canonical BAF chromatin remodeling complex specifies stem cell fate via cell-type-specific co-factor recruitment
Clapier, C. R., Iwasa, J., Cairns, B. R. & Peterson, C. L. Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes. Nat Rev Mol Cell Biol. 18, 407–422 (2017).
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