During their search for food, most insects head specifically for the flowers that promise the highest reward. But how do they know which ones to choose? Researchers from the University of Konstanz and the University of Würzburg have now studied…
Category: 5. Biology
-
Color shortcut reveals bumblebees are efficient decision-makers
-
Multicenter ex vivo evaluation of an α-mannosidase–targeted fluorescent probe for intraoperative margin assessment in breast cancer
Taguchi, M. et al. Detection capability of the Medical Imaging Projection System for sentinel lymph node biopsy in patients with breast cancer with and without neoadjuvant chemotherapy: a retrospective study. Breast Cancer. 32, 834–840 (2025)….
Continue Reading
-
Canonical BAF chromatin remodeling complex specifies stem cell fate via cell-type-specific co-factor recruitment
Clapier, C. R., Iwasa, J., Cairns, B. R. & Peterson, C. L. Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes. Nat Rev Mol Cell Biol. 18, 407–422 (2017).
Continue Reading
-
Sex-specific effects of acetylation on tauopathy in aging htau mice
Chandrashekar, D. V. et al. Alcohol as a Modifiable Risk Factor for Alzheimer’s Disease-Evidence from Experimental Studies. Int. J. Mol. Sci., 24(11), 9492 (2023).
Sullivan, E. V. & Pfefferbaum, A. Alcohol use disorder: neuroimaging evidence for…
Continue Reading
-
Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR
Single-cell transcriptomics defines a hierarchy of TF activity controlling cellular cardiomyocyte response to afterload stress progression
We hypothesized that restoring the balance of endogenous key transcriptional programs disrupted by cellular…
Continue Reading
-
Impact of PSA- versus STN-DBS on effective connectivity in Parkinson’s disease – a 3.0T resting-state fMRI study
Tanner, C. M. & Ostrem, J. L. Parkinson’s disease. N. Engl. J. Med. 391, 442–452 (2024).
Albin, R. L., Young, A. B. & Penney, J. B. The functional anatomy of basal ganglia disorders. Trends…
Continue Reading
-
Integration of circulating tumor DNA data enhances lung cancer prediction in patients with COPD
Safiri, S. et al. Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: Results from the global burden of disease study 2019. BMJ 378, e069679.
Continue Reading
-
Integrative mendelian randomization approaches for therapeutic target prioritisation in immune-mediated diseases
He, M. et al. Immune-Mediated Diseases Associated With Cancer Risks. JAMA Oncol. 8, 209–219 (2022).
El-Gabalawy, H., Guenther, L. C. & Bernstein, C. N. Epidemiology of immune-mediated…
Continue Reading
-
Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitment
Human participants
Sepsis patients and controls were recruited at Tianjin Medical University General Hospital. Sepsis was diagnosed according to the 2016 Sepsis-3 criteria, defined as suspected or confirmed infection (evidenced by clinical signs…
Continue Reading
-
L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability
The pivotal genes correlated with MAC progression were identified
Given the distinct differences in biological behaviors and clinicopathological features between MAC and AC, specific genes related to the clinicopathological features of MAC were…
Continue Reading