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Category: 5. Biology

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  • HPLC based identification of phenolics and biological activities in Elaphomyces mushroom extracts

    HPLC based identification of phenolics and biological activities in Elaphomyces mushroom extracts

  • Singh, D. et al. In Silico molecular screening of bioactive natural compounds of Rosemary essential oil and extracts for Pharmacological potentials against rhinoviruses. Sci. Rep. 14, 17426 (2024).

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  • The Lpp-OmpA-BtaE fusion protein causes a protective immune response against Brucella melitensis in mice

    The Lpp-OmpA-BtaE fusion protein causes a protective immune response against Brucella melitensis in mice

    In this study, the enhanced immunogenic response and protective efficacy of the BtaE antigen against B. melitensishas been demonstrated in a murine model through its incorporation into the Lpp-OmpA-BtaE construct. The integration of computational…

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  • Benchmarking large language models for replication of guideline-based PGx recommendations

    Benchmarking large language models for replication of guideline-based PGx recommendations

  • Coleman JJ, Pontefract SK. Adverse drug reactions. Clin Med. 2016;16:481–5.

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  • Slight SP, Seger DL, Franz C, Wong A, Bates DW. The national cost of adverse drug events resulting from inappropriate…

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  • PPARγ acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding

    PPARγ acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding

  • Chaffer CL, Weinberg RA. How does multistep tumorigenesis really proceed?. Cancer Discov. 2015;5:22–24.

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  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646–74.

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  • Chromosome-level genome assembly of Sinocyclocheilus jii based on PacBio HiFi and Hi-C sequencing

    Chromosome-level genome assembly of Sinocyclocheilus jii based on PacBio HiFi and Hi-C sequencing

    Sampling and genome survey

    A healthy female S. jii weighing 23 g was collected from Fuchuan Yao Autonomous County, Guangxi, China (Fig. 1). After anesthesia with fish anesthetic MS-222, the specimen was immediately dissected. Muscle, heart,…

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  • Vanadyl sulfate restores memory impairment in streptozotocin-induced rat model of sporadic alzheimer’s disease by repressing FoxO1 gene expression

    Vanadyl sulfate restores memory impairment in streptozotocin-induced rat model of sporadic alzheimer’s disease by repressing FoxO1 gene expression

    Escape latency time trials

    Line graph in Fig. 2a shows means of escape latency time (Second) at different time points. The related data are shown in Table 1. There was a significant interaction effect between group and time on escape latency…

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  • A 20-feature radiomic signature of triple-negative breast cancer identifies patients at high risk of death

    A 20-feature radiomic signature of triple-negative breast cancer identifies patients at high risk of death

  • Almansour, N. M. Triple-negative breast cancer: a brief review about epidemiology, risk factors, signaling pathways, treatment and role of artificial intelligence. Front. Mol. Biosci. 9, 836417 (2022).

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  • In vitro and in silico neuroprotective evaluation of new biotransformation metabolites of (-)-α-bisabolol

    In vitro and in silico neuroprotective evaluation of new biotransformation metabolites of (-)-α-bisabolol

    A total of 22 microbial cultures were used in the initial screening of (-)-α-bisabolol (1). Five biotransformation metabolites (2–6) were produced by Cordyceps sinensis ATCC 24400 (2 and 6), Alternaria alternata ATCC 10801 (3) and Aspergillus…

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