Cell culture
HEK293T (American Type Culture Collection (ATCC), CRL-11268) were cultured as recommended by the ATCC. Cell lines tested negative for Mycoplasma and were authenticated by the suppliers.
Modeling of gene-editing outcomes
The inDelphi…
Category: 5. Biology
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Exosomes from liver progenitor cells carrying JAG1 activate notch signaling to promote liver regeneration in PVL rats
Animals
Male Sprague Dawley (SD) rats weighing 200–250 g were obtained from Shanghai Bikai Keyi Biotechnology Co., Ltd. and housed at the Animal Center of Naval Medical University under specific pathogen-free conditions. Care, breeding, and…
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Reticulate allopolyploidy and subsequent dysploidy drive evolution and diversification in the cotton family
Van de Peer, Y., Mizrachi, E. & Marchal, K. The evolutionary significance of polyploidy. Nat. Rev. Genet. 18, 411–424 (2017).
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Jiao, Y. et al. Ancestral polyploidy in seed plants…
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TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells
Plasmacytoid DCs convert into cDC2s on activation
We hypothesized that single-cell multiomics would allow us to track the fate of individual pDCs during activation. To establish a reference framework, we first generated a panDC map capturing the…
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Morphological profiling reveals neuroprotection via mitochondrial uncoupling in human dopaminergic neurons
Origin of iPSC lines and differentiation into mDA neurons
SNCA iPSC lines (originally named AST23 and AST23-2KO) were provided and generated by Dr. Tilo Kunath from The University of Edinburgh. The parental cell line AST23 was first described in…
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A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses
A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses
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Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins
Cell lines
Human leukemia cell lines HL60, Kasumi, U937, and MV4-11 were purchased from National Collection of Authenticated Cell Cultures (Shanghai, China). Human leukemia KG1 cells was purchased from ATCC (Manassas, Maryland, USA). OCI-AML3 and…
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The brain drain puts aging myelin in deep trouble
The brain drain puts aging myelin in deep trouble
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Response to ‘The puzzle of biologics manufacturing platform patents’
Amgen is the leading manufacturer of both innovative biologics and biosimilar medicines and is uniquely positioned to respond to the “puzzle” of unsupported assertions in the March Patent Feature by Jefferson et al.1. Contrary to their…
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Correction: TIGIT antibody with PVR competitive ability enhances cancer immunotherapy and capable of eliciting anti-tumour immune memory
Cite this article
Yu, H., Jin, S., Zeng, M. et al. Correction: TIGIT antibody with PVR competitive ability enhances cancer immunotherapy and capable of eliciting anti-tumour immune memory.
Br J Cancer (2025)….Continue Reading