Category: 5. Biology

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  • Single nucleus RNA sequencing profile analysis to reveal cell type specific common molecular drivers of Parkinson’s disease and therapeutic agents

    Single nucleus RNA sequencing profile analysis to reveal cell type specific common molecular drivers of Parkinson’s disease and therapeutic agents

  • Reeve, A., Simcox, E. & Turnbull, D. Ageing and parkinson’s disease: why is advancing age the biggest risk factor? Ageing Res. Rev. 14, 19–30 (2014).

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  • Curcumin exerts neuroprotective effects on proliferation of neural stem cells in vitro and APP/PS1 mouse model in vivo

    Curcumin exerts neuroprotective effects on proliferation of neural stem cells in vitro and APP/PS1 mouse model in vivo

    Primary NSC culture and expansion

    Neural stem cells (NSCs) were cultured to generate neurospheres according to the protocols established by Reynolds and Weiss39. Telencephalic tissue was isolated from embryonic day 16 (E16) mice and subjected to…

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  • Targeting Langerhans cells via skin delivery of HIV Envelope enhances the antibody response to vaccination

    Targeting Langerhans cells via skin delivery of HIV Envelope enhances the antibody response to vaccination

    Vaccine constructs and formulations

    The αLang.Env vaccine constructs have been designed and produced as previously published34. Briefly, the anti-Langerin mAb was developed in-house (clone 4C731, GenBank sequences JX002668, JX002669) and…

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  • Octenidine effectively reduces Candida auris colonisation on human skin

    Octenidine effectively reduces Candida auris colonisation on human skin

  • Ingham, C. J. et al. Rapid susceptibility testing and microcolony analysis of Candida spp. cultured and imaged on porous aluminum oxide. PLoS ONE 7, 33818. https://doi.org/10.1371/journal.pone.0033818 (2012).

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  • Decoding cell fate: human models reveal how SMAD2 variants shape development

    The ability to sequence genomes at scale has revealed a vast landscape of rare and de novo variants in patients with congenital heart disease (CHD) and other complex disorders. Yet how do we decode the functional impact of these variants,…

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  • Author Correction: Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis

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  • Metabolomic profiles impacted by brief mindfulness intervention with contributions to improved health

    Metabolomic profiles impacted by brief mindfulness intervention with contributions to improved health

  • Hart, W. Art of Living: Vipassana Meditation (2011).

  • Tang, Y. Y., Hölzel, B. K. & Posner, M. I. The neuroscience of mindfulness meditation. Nat. Rev. Neurosci. 16, 213–225 (2015).

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  • How leukocytes push their way through tissues

    How leukocytes push their way through tissues

    How leukocytes push their way through tissues

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  • Publisher Correction: IL-33/ST2 drives inflammatory pain via CCL2 signaling and activation of TRPV1 and TRPM8

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