Category: 5. Biology

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  • Survival benefit associated with first-line androgen receptor pathway inhibitors for de novo metastatic castration-sensitive prostate cancer

    Survival benefit associated with first-line androgen receptor pathway inhibitors for de novo metastatic castration-sensitive prostate cancer

  • Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74:12–49.

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  • Piombino C, Oltrecolli M, Tonni E, Pirola M, Matranga R, Baldessari C, et al. De novo…

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  • Biotin/sulfasalazine combination therapy alleviates acetic acid-induced ulcerative colitis in rats via modulation of S1PR1/NF-κB/IL-23/STAT3/COX-2 axis

    Biotin/sulfasalazine combination therapy alleviates acetic acid-induced ulcerative colitis in rats via modulation of S1PR1/NF-κB/IL-23/STAT3/COX-2 axis

  • Gisbert, J. P. & Chaparro, M. Clinical usefulness of proteomics in inflammatory bowel disease: A comprehensive review. J. Crohns Colitis 13(3), 374–384 (2019).

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  • Jackson, B. & De…

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  • Spatiotemporal H2O2 flashes coordinate actin cytoskeletal remodeling and regulate cell migration and wound healing

    Spatiotemporal H2O2 flashes coordinate actin cytoskeletal remodeling and regulate cell migration and wound healing

    Reagents

    The following reagents were used: BAPTA-AM (196419), diphenyleneiodonium chloride (DPI) (300260), Calbiochem; phorbol 12-myristate 13-acetate (PMA) (P8139), thapsigargin (T9033), LPS E.coli (L2630), homovanillic acid (306-08-1),…

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  • Comparing the precision of two digital PCR applications for copy number comparisons in protists

    Comparing the precision of two digital PCR applications for copy number comparisons in protists

  • Hutchins, D. A. & Fu, F. Microorganisms and ocean global change. Nat. Microbiol. 2, 1–11 (2017).

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  • Tilman, D. et al. The influence of functional diversity and composition on ecosystem…

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  • Spatially constrained disulfide bond shuffling delays insulin aggregation and enhances neurotoxicity

    Spatially constrained disulfide bond shuffling delays insulin aggregation and enhances neurotoxicity

    Spatial distance-confined Insulin DBS

    We previously have demonstrated the distance confinement for bicarbonate heating-induced DBS products likely ranges from 2 Å (the length for disulfide bond) to over 9 Å21. For insulin, the crystal…

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  • Contribution of phenolic compounds and hormones in antioxidant defense responses of wild and cultivated barley genotypes under drought and heat stress

    Contribution of phenolic compounds and hormones in antioxidant defense responses of wild and cultivated barley genotypes under drought and heat stress

    The influence of environmental conditions on traits

    The results of the combined analysis of variance (ANOVA) are summarized in Table 1. Significant effects were observed for genotype, irrigation regime (drought), planting date (heat), and their…

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  • Author Correction: Human HDAC6 senses valine abundancy to regulate DNA damage

  • These authors contributed equally: Jiali Jin, Tong Meng, Yuanyuan Yu, Shuheng Wu

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