Mining the Snaptron database for alternative splicing events of interest
The Snaptron database48 includes compiled exon-exon splice junction information across samples from four human RNA-Seq sample databases: SRA52, GTEx53, TCGA54, and ENCODE56….
Category: 5. Biology
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Dissecting the contribution of Kup and KimA to Enterococcus faecalis potassium homeostasis
Genomic context and mobile element characterization
Based on our previous study demonstrating the influence of IS6770 on kup gene expression in JH2-2 strain, we conducted a comparative analysis of the genomic region between the kimA and kup gene…
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The origin of modern North Africans as depicted by a massive survey of mitogenomes
We evaluated the mitogenome variation of 776 (733 modern and 43 ancient) North African subjects from Morocco, Algeria, Tunisia, Libya, and Egypt. The dataset, which includes 238 newly sequenced modern mitogenomes of North African origin together…
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A structural switch reveals how to disarm USP30 and unlock mitophagy
A structural switch reveals how to disarm USP30 and unlock mitophagy
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Dissolving stress granules | Nature Chemical Biology
Uechi, H. et al. Nat. Chem. Biol. https://doi.org/10.1038/s41589-025-01893-5 (2025).
Bravo-Jimenez, M. A., Sharma, S. & Karimi-Abdolrezaee, S. Mol. Neurodegener. 20, 20 (2025).
Google…
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Neurophysiological evidence of human hippocampal longitudinal differentiation in associative memory
Ranganath, C. Binding items and contexts: The cognitive neuroscience of episodic memory. Curr. Directions Psychological Sci. 19, 131–137 (2010).
Yim, H., Dennis, S. J. & Sloutsky, V. M. The…
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An enzyme for high-yield, ATP-driven C-terminal thioester generation
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Frazier, C. L. et al. Engineered reactivity of a bacterial E1-like enzyme enables…
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Aberrant protein translation promotes T cell exhaustion
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Liu, Y. et al. LARP4-mediated hypertranslation drives T cell dysfunction in tumors….
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Triple-effect correction for Cell Painting data with contrastive and domain-adversarial learning
This research does not involve human participants, animal subjects, or the use of biological samples requiring institutional ethics approval. All relevant ethical regulations were followed.
Overview of cpDistiller
cpDistiller consists of three main…
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Exosome- transported FER inhibitor suppresses progression of diffuse large B-cell lymphoma via regulating AJUBA/Hippo axis
Patients
Paraffin-embedded samples of 50 primary DLBCL patients and 30 reactive hyperplasia patients in Shandong Provincial Hospital between 2014 and 2019 were collected. Samples of reactive hyperplasia were used as controls. Peripheral blood,…
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