Category: 5. Biology

VCU Massey Comprehensive Cancer Center is the first site in the United States to be activated in a global Phase 2a clinical trial evaluating PTX-100 (AKA GGTI-2418), a first-in-class small molecule inhibitor of geranylgeranyl…

A new study led by Stephen D. Nimer, M.D., director of Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, shows how a key molecule regulates the generation of new blood cells, a process…

A total of 5110 patients were enrolled to the study, among whom 117 presented with BrM either at initial presentation or during their follow-up. The baseline characteristics of the entire cohort are presented in Table 1. Median age at diagnosis…

Subject

Two original germ-free strains BALB/cAnSlac (BC) and Kunming (KM) were bred in Shanghai Tenth People’s Hospital, Tenth People’s Hospital of TongJi University in Shanghai, China. The SPF NOD/SCID Il2rg^–/– (NSG) strain was purchased…

snGESTALT analysis suggests a developmental relationship between muscle and kidney

Consistent with the prior observation in Sandkhol Carp, we found that zebrafish NPCs, which are fluorescently labelled in the Tg(lhx1a:EGFP) transgenic line^7,16,…

Study design and participants

This phase 2 single-arm, open-label trial (ClinicalTrials.gov NCT05348213) adopted a prospective cohort design. Enrollment was restricted to R/R DLBCL patients. Participant inclusion criteria included: age 18–75…