Category: 5. Biology

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  • Spatiotemporal dynamics of benzylisoquinoline alkaloid gene expression and co-expression networks during Papaver Somniferum developmental stages

    Spatiotemporal dynamics of benzylisoquinoline alkaloid gene expression and co-expression networks during Papaver Somniferum developmental stages

    Transcriptome sequencing and gene expression analysis

    This study performed 150 bp paired-end transcriptome sequencing on roots, stems, leaves, and fruits (ovaries) of P. somniferum across developmental stages, generating 2.32 billion raw reads….

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  • DynaTag for efficient mapping of transcription factors in low-input samples and at single-cell resolution

    DynaTag for efficient mapping of transcription factors in low-input samples and at single-cell resolution

    Ethical statement

    The patient sample S0273026 was collected under approved protocols of the institutional review board (IRB, ID: 19-1164) of the University of Cologne and provided written informed consent to share potentially identifying…

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  • Myeloid cells in chronic liver inflammation

    Myeloid cells in chronic liver inflammation

  • Marcellin P, Kutala BK. Liver diseases: a major, neglected global public health problem requiring urgent actions and large-scale screening. Liver Int. 2018;38:2–6.

    PubMed 

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  • Younossi ZM, Wong…

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  • Decoding the striatum of drug-naive patients with obsessive-compulsive disorder: a transcriptome and longitudinal functional magnetic resonance imaging study

    Decoding the striatum of drug-naive patients with obsessive-compulsive disorder: a transcriptome and longitudinal functional magnetic resonance imaging study

  • Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci. 1986;9:357–81.

    CAS 

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  • Di Martino A, Scheres…

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  • SNP rs615552 and lncRNA CDKN2B-AS1 influence brain cancer pathogenesis through multi-omic mechanisms

    SNP rs615552 and lncRNA CDKN2B-AS1 influence brain cancer pathogenesis through multi-omic mechanisms

    Multi-omics colocalization analysis reveals key genetic variants in brain cancer

    eQTL analysis indicates that CDKN2A, CDKN2B, and CDKN2B-AS1 co-locate with brain cancer(Fig. 1A, B, C). In the BrainMeta_cis_eQTL dataset, rs615552_AL359922.1 shows…

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  • A Novel ‘Sense’ Linking the Gut to the Brain is Discovered

    A Novel ‘Sense’ Linking the Gut to the Brain is Discovered

    The gut is sometimes referred to as a second brain, since it harbors its own nervous system, which is known as the enteric nervous system. The gut is not only directly linked to the brain through the nervous…

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