Category: 5. Biology

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  • CD142-positive synovial fibroblasts drive meniscus destruction in rheumatoid arthritis

    CD142-positive synovial fibroblasts drive meniscus destruction in rheumatoid arthritis

    Human subjects research

    This study does not involve sex-based analysis, and sex was not considered in the study design, since RA involves both. Therefore, for human participants, both male and female patients were included. All patients included…

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  • Biomechanical control of vascular morphogenesis by the surrounding stiffness

    Biomechanical control of vascular morphogenesis by the surrounding stiffness

    All genetic modification experiments in this study were approved by the Gene Recombination Experiment Committee established based on the University of Miyazaki internal regulations. All animal experiments using mice were carried out in accordance…

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  • Targeting oxidative stress and metal imbalance in cerebral ischemia: the neuroprotective role of sodium valproate

    Targeting oxidative stress and metal imbalance in cerebral ischemia: the neuroprotective role of sodium valproate

    Surgery and treatments

    For this purpose, a total of thirty-two male albino Wistar rats (220–230 g) were collected from the Elazig Veterinary Control Institute Animal Experiments Department. The animals were kept in controlled conditions…

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  • The value of prealbumin in predicting post hepatectomy liver failure for patients with hepatocellular carcinoma undergoing major hepatectomy

    The value of prealbumin in predicting post hepatectomy liver failure for patients with hepatocellular carcinoma undergoing major hepatectomy

    This study aims to explore the value of prealbumin and its comprehensive indicator, the prealbumin-Bilirubin (preALBI) score, in predicting PHLF. A total of 466 patients were included in the study and divided into two groups based on the cut-off…

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  • Agent-based simulation of cortical microtubule band movement in arabidopsis zygotes

    Agent-based simulation of cortical microtubule band movement in arabidopsis zygotes

    The CMT band moves upward with a speed of 1.5 ± 1.2 μm/hour and a width of 5.2 ± 2.4 μm

    To determine the mechanism by which the CMT band moves to maintain its position as the zygote expands, we first quantified the width and movement…

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  • Combatting virulent gut bacteria by inhibiting the biosynthesis of a two-component lanthipeptide toxin

    Combatting virulent gut bacteria by inhibiting the biosynthesis of a two-component lanthipeptide toxin

    General methods

    All reagents used for chemical synthesis were purchased from Sigma Aldrich, Chem-Impex and CombiBlocks. N,N-Dimethylformamide (DMF) and dichloromethane (DCM) were dried over 3 Å molecular sieves before use. Chromatography was…

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  • Leveraging single-cell spatial transcriptomics and connectomics to resolve brain circuit function in psychiatry

    Understanding how brain circuits contribute to neuropsychiatric disorders remains a major challenge, in part because functionally distinct neurons are frequently intermingled within densely interconnected networks, making it difficult to assign…

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  • Oxidative stress, apoptosis and proliferation in uterus of piglets fed by sow or formula after ex vivo endocrine compound exposure

    Oxidative stress, apoptosis and proliferation in uterus of piglets fed by sow or formula after ex vivo endocrine compound exposure

  • Lauretta, R., Sansone, A., Sansone, M., Romanelli, F. & Appetecchia, M. Endocrine disrupting chemicals: effects on endocrine glands. Front. Endocrinol. (Lausanne). 10, 178 (2019).

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