Saad, S. & Jarosz, D. F. Protein self-assembly: a new frontier in cell signaling. Curr. Opin. Cell Biol. 69, 62–69 (2021).
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Category: 5. Biology
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Structural basis and regulation of GSDME pore formation
Shi, J., Gao, W. & Shao, F. Pyroptosis: gasdermin-mediated programmed necrotic cell death. Trends Biochem. Sci. 42, 245–254 (2017).
Tan, Y. et al. Pyroptosis: a new paradigm of cell death for…
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CRISPR-based mutagenesis of lipopolysaccharide biosynthesis genes in Leptospira interrogans reveals gene essentiality and confirms the role of an O-antigen polymerase
Bharti, A. R. et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect. Dis. 3 (12), 757–771 (2003).
Putz, E. J. & Nally, J. E. Investigating the Immunological and…
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Integrated UPLC, bioinformatics, and in vitro analyses reveal Yiqihuoxue decoction (GSC) alleviates vascular aging by promoting autophagy
Partridge, L., Deelen, J. & Slagboom, P. E. Facing up to the global challenges of ageing. Nature 561, 45–56 (2018).
Ungvari, Z., Kaley, G., de Cabo, R., Sonntag, W. E. & Csiszar, A….
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Author Correction: Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Adaptable, quantitative CRISPR/Cas12a-based assay for cytomegalovirus DNA in infant saliva
Schleiss, R. M. Congenital cytomegalovirus infection: Molecular mechanisms mediating viral pathogenesis. Infect. Disord. Drug Targets 11(5), 449–465 (2011).
La Rosa, C. & Diamond, D. J. The…
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A catalog of LINE-1 insertions
Long interspersed element-1 (LINE-1) retrotransposons are the most abundant transposable elements in mammalian genomes. Apart from mobilizing sequences such as Alu elements, LINE-1 can also produce chimeric insertions with some RNA species, but a…
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Computational screening of AI-derived cyclotides as putative VEGFR2 binders for wound-site angiogenesis
Okonkwo, U. A. et al. Compromised angiogenesis and vascular Integrity in impaired diabetic wound healing. PLOS ONE. 15, e0231962. https://doi.org/10.1371/journal.pone.0231962 (2020).
Okonkwo,…
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CCND3 enhancer variant reduces malaria risk
Susceptibility to malaria varies across individuals and populations, but the underlying genetic and physiological mechanisms are incompletely understood. Marini et al. closely studied the role of the variant rs112233623-T in the context of…
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