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  • In situ structure determination of conformationally flexible targets using nextPYP

    In situ structure determination of conformationally flexible targets using nextPYP

  • Lucas, B. A. et al. Locating macromolecular assemblies in cells by 2D template matching with cisTEM. eLife 10, e68946 (2021).

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  • Cheng, J. et al. Determining…

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  • Insights into type IX secretion from PorKN cogwheel structure bound to PorG and attachment complexes

    Insights into type IX secretion from PorKN cogwheel structure bound to PorG and attachment complexes

    High-resolution structure of the PorKN rings

    Previously, we purified the PorKNG complex from P. gingivalis and demonstrated that it forms large, 50 nm ring-shaped structures22. However, due to one preferred orientation on the EM grid and protein…

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  • Research on deep learning model for stock prediction by integrating frequency domain and time series features

    Research on deep learning model for stock prediction by integrating frequency domain and time series features

    Dataset introduction

    This study selects historical trading data from the NASDAQ and NYSE between January 2013 and August 2017, including five core features (open, high, low, close, and volume). A sliding window mechanism with a lookback of 16 days…

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  • Jahn-Teller effect for controlling quantum correlations in hexanuclear Fe $$^{3+}$$ magnets

    Jahn-Teller effect for controlling quantum correlations in hexanuclear Fe $$^{3+}$$ magnets

    Ground-state phase diagram and magnetization

    We present the ground-state phase diagram of the model defined by the Hamiltonian (1) using pie charts in Fig. 2a, in a spanned parameter space \((J_2, B) \in ([0, 60]; [0, 80])\) for four…

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  • Author Correction: Meta-prediction of coronary artery disease risk

  • Scripps Research Translational Institute, La Jolla, CA, USA

    Shang-Fu Chen, Hossein Javedani Sadaei, Ahmed Khattab, Corneliu Henegar, Nathan E. Wineinger, Evan D. Muse & Ali Torkamani

  • Department of Integrative Structural and Computational…

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  • Digital twins as self-models for intelligent structures

    Digital twins as self-models for intelligent structures

    Digital twin architecture and implementation

    The overall architecture of the digital twin is shown schematically in Fig. 3. In this architecture, the digital twin is composed of three main parts that enable a connection between the physical twin…

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  • Tiny Australian predator defies drought to recover from near-extinction

    Tiny Australian predator defies drought to recover from near-extinction

    • RESEARCH HIGHLIGHT

    Rat-sized carnivore called the ampurta makes speedy…

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  • O-GlcNAc transferase plays dual antiviral roles by integrating innate immunity and lipid metabolism

    O-GlcNAc transferase plays dual antiviral roles by integrating innate immunity and lipid metabolism

  • Ablasser, A. & Hur, S. Regulation of cGAS- and RLR-mediated immunity to nucleic acids. Nat. Immunol. 21, 17–29 (2020).

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  • Brubaker, S. W., Bonham, K. S., Zanoni, I. & Kagan, J. C….

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